KEGG   ORTHOLOGY: K13559
Entry
K13559            Tight     KO                                     
Symbol
btrJ
Name
[BtrI acyl-carrier protein]--L-glutamate ligase [EC:6.2.1.39]
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R08905  L-glutamate:[acyl-carrier protein] ligase (ADP-forming)
R08906  L-glutamate:4-aminobutyryl-[acp] ligase (ADP-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K13559  btrJ; [BtrI acyl-carrier protein]--L-glutamate ligase
Enzymes [BR:ko01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.39  [butirosin acyl-carrier protein]---L-glutamate ligase
     K13559  btrJ; [BtrI acyl-carrier protein]--L-glutamate ligase
Genes
AG: BAE07074(btrJ)
Reference
  Authors
Kudo F, Numakura M, Tamegai H, Yamamoto H, Eguchi T, Kakinuma K
  Title
Extended sequence and functional analysis of the butirosin biosynthetic gene cluster in Bacillus circulans SANK 72073.
  Journal
J Antibiot (Tokyo) 58:373-9 (2005)
DOI:10.1038/ja.2005.47
  Sequence
Reference
  Authors
Kudo F, Eguchi T
  Title
Biosynthetic enzymes for the aminoglycosides butirosin and neomycin.
  Journal
Methods Enzymol 459:493-519 (2009)
DOI:10.1016/S0076-6879(09)04620-5
LinkDB

DBGET integrated database retrieval system