KEGG   ORTHOLOGY: K13608
Entry
K13608            Tight     KO                                     
Symbol
SNO
Name
senecionine N-oxygenase [EC:1.14.13.101]
Pathway
map00960  Tropane, piperidine and pyridine alkaloid biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R07373  senecionine,NADPH:oxygen oxidoreductase (N-oxide-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00960 Tropane, piperidine and pyridine alkaloid biosynthesis
    K13608  SNO; senecionine N-oxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.101  senecionine N-oxygenase
     K13608  SNO; senecionine N-oxygenase
Other DBs
GO: 0033784
Genes
AG: CAD12369(SNO)
Reference
PMID:11972041
  Authors
Naumann C, Hartmann T, Ober D
  Title
Evolutionary recruitment of a flavin-dependent monooxygenase for the detoxification of host plant-acquired pyrrolizidine alkaloids in the alkaloid-defended arctiid moth Tyria jacobaeae.
  Journal
Proc Natl Acad Sci U S A 99:6085-90 (2002)
DOI:10.1073/pnas.082674499
  Sequence
[ag:CAD12369]
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