KEGG ORTHOLOGY: K13667

ORTHOLOGY: K13667

Entry

K13667                      KO

Symbol

POGLUT1, RUMI, KTELC1

Name

EGF-domain serine glucosyl/xylosyltransferase [EC:2.4.1.376 2.4.2.63]

Pathway

map00514

Other types of O-glycan biosynthesis

Reaction

R09315

Disease

H00593

Limb-girdle muscular dystrophy

H00944

Dowling-Degos disease

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00514 Other types of O-glycan biosynthesis
    K13667  POGLUT1, RUMI, KTELC1; EGF-domain serine glucosyl/xylosyltransferase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K13667  POGLUT1, RUMI, KTELC1; EGF-domain serine glucosyl/xylosyltransferase
Enzymes [BR:ko01000]
2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.376  EGF-domain serine glucosyltransferase
     K13667  POGLUT1, RUMI, KTELC1; EGF-domain serine glucosyl/xylosyltransferase
   2.4.2  Pentosyltransferases
    2.4.2.63  EGF-domain serine xylosyltransferase
     K13667  POGLUT1, RUMI, KTELC1; EGF-domain serine glucosyl/xylosyltransferase
Glycosyltransferases [BR:ko01003]
O-Glycan biosynthesis
  O-linked Glc type
   K13667  POGLUT1, RUMI, KTELC1; EGF-domain serine glucosyl/xylosyltransferase

Other DBs

CAZy:

GT90

Genes

HSA:	56983(POGLUT1)

PTR:	460605(POGLUT1)

PPS:	100996033(POGLUT1)

GGO:	101148987(POGLUT1)

PON:	100442484(POGLUT1)

NLE:	100601138(POGLUT1)

HMH:	116466911(POGLUT1)

MCC:	712357(POGLUT1)

MCF:	102140463(POGLUT1)

MTHB:

126947747

MNI:	105470341(POGLUT1)

CSAB:

103228230(POGLUT1)

CATY:

105589726(POGLUT1)

PANU:

101020502(POGLUT1)

TGE:	112619466(POGLUT1)

MLEU:

105544623(POGLUT1)

RRO:	104657614(POGLUT1)

RBB:	108531821(POGLUT1)

TFN:	117083471(POGLUT1)

PTEH:

111543775(POGLUT1)

CANG:

105510726(POGLUT1)

CJC:	100392996(POGLUT1)

SBQ:	101028421(POGLUT1)

CIMI:

108296446(POGLUT1)

CSYR:

103254568(POGLUT1)

MMUR:

105879924(POGLUT1)

LCAT:

123630515(POGLUT1)

PCOQ:

105808319(POGLUT1)

OGA:	100964166(POGLUT1)

MMU:	224143(Poglut1)

MCAL:

110311390(Poglut1)

MPAH:

110329469(Poglut1)

RNO:	288091(Poglut1)

MCOC:

116085903(Poglut1)

ANU:	117718090(Poglut1)

MUN:	110555395(Poglut1)

CGE:	100760325(Poglut1)

MAUA:

101841266(Poglut1)

PROB:

127227163(Poglut1)

PLEU:

114701491(Poglut1)

MORG:

121461999(Poglut1)

MFOT:

126505845

AAMP:

119825319(Poglut1)

NGI:	103741939(Poglut1)

HGL:	101707033(Poglut1)

CPOC:

100736113(Poglut1)

CCAN:

109694532(Poglut1)

DORD:

105987916(Poglut1)

DSP:	122098547(Poglut1)

PLOP:

125351729(Poglut1)

NCAR:

124992920

MMMA:

107136291(Poglut1)

OCU:

100344082

OPI:	101534837(POGLUT1)

TUP:	102478881(POGLUT1)

GVR:	103598139(POGLUT1)

CFA:	487993(POGLUT1)

CLUD:

112677830(POGLUT1)

VVP:	112913459(POGLUT1)

VLG:	121471241(POGLUT1)

NPO:	129503622(POGLUT1)

AML:	100480912(POGLUT1)

UMR:	103678843(POGLUT1)

UAH:	113251857(POGLUT1)

UAR:	123784033(POGLUT1)

ELK:

111147444

LLV:

125097742

MPUF:

101674307(POGLUT1)

MNP:	132012204(POGLUT1)

MLK:	131825087(POGLUT1)

NVS:	122908531(POGLUT1)

ORO:	101386979(POGLUT1)

EJU:	114214817(POGLUT1)

ZCA:	113918644(POGLUT1)

MLX:	118007071(POGLUT1)

NSU:	110582449(POGLUT1)

LWW:	102742937(POGLUT1)

FCA:	101088101(POGLUT1)

PYU:	121036275(POGLUT1)

PCOO:

112849871(POGLUT1)

PBG:	122491471(POGLUT1)

PVIV:

125175426(POGLUT1)

LRUF:

124526775

PTG:	102972728(POGLUT1)

PPAD:

109266432(POGLUT1)

PUC:

125921780

AJU:

106968287

HHV:	120225967(POGLUT1)

BTA:	511862(POGLUT1)

BOM:	102277916(POGLUT1)

BIU:	109576903(POGLUT1)

BBUB:

102406475(POGLUT1)

BBIS:

104992473(POGLUT1)

CHX:	102191273(POGLUT1)

OAS:	101105708(POGLUT1)

BTAX:

128053862(POGLUT1)

ODA:	120871250(POGLUT1)

CCAD:

122445579(POGLUT1)

MBEZ:

129560291(POGLUT1)

SSC:	100525611(POGLUT1)

CFR:	102523608(POGLUT1)

CBAI:

105081589(POGLUT1)

CDK:	105090329(POGLUT1)

VPC:	102537660(POGLUT1)

BACU:

103003776(POGLUT1)

BMUS:

118894693(POGLUT1)

LVE:	103085383(POGLUT1)

OOR:	101279837(POGLUT1)

DLE:	111167187(POGLUT1)

PCAD:

102976502(POGLUT1)

PSIU:

116753361(POGLUT1)

NASI:

112413462(POGLUT1)

ECB:	100071030(POGLUT1)

EPZ:	103547415(POGLUT1)

EAI:	106823701(POGLUT1)

MYB:	102262926(POGLUT1)

MYD:	102752908(POGLUT1)

MMYO:

118676595(POGLUT1)

MLF:	102425666(POGLUT1)

PKL:	118724329(POGLUT1)

EFUS:

103290710(POGLUT1)

MNA:	107527335(POGLUT1)

DRO:	112320557(POGLUT1)

SHON:

118986584(POGLUT1)

AJM:	119059192(POGLUT1)

PDIC:

114490862(POGLUT1)

PHAS:

123827490(POGLUT1)

MMF:	118617745(POGLUT1)

PPAM:

129069649(POGLUT1) 129082265

HAI:	109388471(POGLUT1)

RFQ:	117013247(POGLUT1)

PALE:

102880714(POGLUT1)

PGIG:

120586655(POGLUT1)

PVP:	105302432(POGLUT1)

RAY:	107508364(POGLUT1)

MJV:	108392243(POGLUT1)

TOD:	119257496(POGLUT1)

SARA:

101537818(POGLUT1)

SETR:

126026211(POGLUT1)

LAV:	100661725(POGLUT1)

TMU:

101351318

ETF:	101663934(POGLUT1)

DNM:	101426603(POGLUT1)

MDO:	100016192(POGLUT1)

GAS:	123239479(POGLUT1)

SHR:	100918363(POGLUT1)

AFZ:

127554103

PCW:	110208064(POGLUT1)

OAA:	103167158(POGLUT1)

GGA:	418455(POGLUT1)

PCOC:

116242023(POGLUT1)

MGP:	100541132(POGLUT1)

CJO:	107322048(POGLUT1)

TPAI:

128090969(POGLUT1)

LMUT:

125684857(POGLUT1)

NMEL:

110401460(POGLUT1)

APLA:

101800875(POGLUT1)

ACYG:

106039966(POGLUT1)

CATA:

118245015(POGLUT1)

AFUL:

116499011(POGLUT1)

TGU:	100217574(POGLUT1)

LSR:	110476510(POGLUT1)

SCAN:

103818416(POGLUT1)

PMOA:

120504041(POGLUT1)

OTC:	121344734(POGLUT1)

PRUF:

121360388(POGLUT1)

GFR:	102041454(POGLUT1)

FAB:	101814002(POGLUT1)

OMA:	130256574(POGLUT1)

PHI:	102100422(POGLUT1)

PMAJ:

107212428(POGLUT1)

CCAE:

111943579(POGLUT1)

CCW:	104689442(POGLUT1)

CBRC:

103613727(POGLUT1)

ETL:	114059604(POGLUT1)

ZAB:	102069592(POGLUT1)

ZLE:	135454799(POGLUT1)

ACHL:

103798995(POGLUT1)

SVG:	106857013(POGLUT1)

MMEA:

130588924(POGLUT1)

HRT:	120748895(POGLUT1)

FPG:	101919362(POGLUT1)

FCH:	102049145(POGLUT1)

CLV:	102092788(POGLUT1)

EGZ:	104123016(POGLUT1)

NNI:	104015008(POGLUT1)

PCRI:

104037160(POGLUT1)

PLET:

104614461(POGLUT1)

EHS:	104504040(POGLUT1)

PCAO:

104039437(POGLUT1)

ACUN:

113475980(POGLUT1)

TALA:

104358498(POGLUT1)

PADL:

103916889(POGLUT1)

AFOR:

103895007(POGLUT1)

ACHC:

115343537(POGLUT1)

HALD:

104317415(POGLUT1)

HLE:	104831819(POGLUT1)

AGEN:

126049023

GCL:

127029472

CCRI:

104154964(POGLUT1)

CSTI:

104555340(POGLUT1)

CMAC:

104473426(POGLUT1)

MUI:	104533748(POGLUT1)

BREG:

104629544(POGLUT1)

FGA:	104071060(POGLUT1)

GSTE:

104256770(POGLUT1)

LDI:	104352334(POGLUT1)

MNB:	103771390(POGLUT1)

OHA:	104337367(POGLUT1)

NNT:	104399575(POGLUT1)

SHAB:

115601512(POGLUT1)

DPUB:

104299528(POGLUT1)

PGUU:

104458130(POGLUT1)

ACAR:

104526605(POGLUT1)

CPEA:

104395775(POGLUT1)

CVF:	104290928(POGLUT1)

RTD:	128902032(POGLUT1)

CUCA:

104056026(POGLUT1)

TEO:	104370222(POGLUT1)

BRHI:

104488053(POGLUT1)

AAM:	106490712(POGLUT1)

AROW:

112974465(POGLUT1)

NPD:	112948253(POGLUT1)

TGT:	104577454(POGLUT1)

DNE:	112979297(POGLUT1)

SCAM:

104149203(POGLUT1)

ASN:	102370297(POGLUT1)

AMJ:	102567059(POGLUT1)

CPOO:

109324962(POGLUT1)

GGN:	109302342(POGLUT1)

PSS:	102453336(POGLUT1)

CMY:	102931530(POGLUT1)

CCAY:

125644773(POGLUT1)

DCC:	119841301(POGLUT1)

CPIC:

101932750(POGLUT1)

TST:	117888540(POGLUT1)

CABI:

116839124(POGLUT1)

MRV:	120404839(POGLUT1)

ACS:	100562217(poglut1)

ASAO:

132771952(POGLUT1)

PVT:	110088504(POGLUT1)

SUND:

121927149(POGLUT1)

PBI:	103059086(POGLUT1)

PMUR:

107289023(POGLUT1)

CTIG:

120303890(POGLUT1)

TSR:	106557375(POGLUT1)

PGUT:

117663818(POGLUT1)

APRI:

131200281(POGLUT1)

PTEX:

113436333(POGLUT1)

NSS:	113409744(POGLUT1)

VKO:	123029452(POGLUT1)

PMUA:

114595966(POGLUT1)

PRAF:

128412898(POGLUT1)

ZVI:	118085544(POGLUT1)

HCG:	128352495(POGLUT1)

GJA:	107117554(POGLUT1)

STOW:

125431847(POGLUT1)

EMC:	129325944(POGLUT1)

XLA:	108707382(poglut1.L) 446695(poglut1.S)

XTR:	493476(poglut1)

NPR:	108803675(POGLUT1)

RTEM:

120921634(POGLUT1)

BBUF:

120994300(POGLUT1)

BGAR:

122922824(POGLUT1)

MUO:	115470601(POGLUT1)

GSH:	117359209(POGLUT1)

DRE:	641495(poglut1)

SRX:	107739820 107742654(poglut1)

SANH:

107700102(poglut1)

SGH:	107552365 107552368 107588837(poglut1)

CCAR:

109083311 109093877

CAUA:

113044357

CGIB:

127949653

PTET:

122349514(poglut1)

LROH:

127170415(poglut1)

OMC:	131546047(poglut1)

PPRM:

120495527

RKG:

130087802

MAMB:

125272295(poglut1)

CIDE:

127514270

MASI:

127443718

TROS:

130555615(poglut1)

TDW:	130434204(poglut1)

MANU:

129444203(poglut1)

IPU:

108259071

IFU:	128602156(poglut1)

PHYP:

113537643(poglut1)

SMEO:

124377779(poglut1)

TFD:	113648659(poglut1)

TVC:	132839659(poglut1)

TRN:	134328327(poglut1)

AMEX:

103033884(poglut1)

CMAO:

118798258(poglut1)

EEE:

113580326

CHAR:

105893299(poglut1)

TRU:	101073599(poglut1)

TFS:	130522169(poglut1)

TNG:	GSTEN00019585G001

LCO:	104937494(poglut1)

NCC:	104961748(poglut1)

TBEN:

117498987(poglut1)

CGOB:

115019011(poglut1)

PGEO:

117458282(poglut1)

GACU:

117546680(poglut1)

EMAC:

134860621(poglut1)

ELY:	117249764(poglut1)

EFO:	125885110(poglut1)

PLEP:

121962835(poglut1)

SLUC:

116044591(poglut1)

ECRA:

117939288(poglut1)

ESP:	116673834(poglut1)

PFLV:

114550792(poglut1)

GAT:	120820785(poglut1)

PPUG:

119222474(poglut1)

AFB:	129111879(poglut1)

CLUM:

117743228(poglut1)

PSWI:

130191512(poglut1)

MSAM:

119901475(poglut1)

SCHU:

122872262(poglut1)

CUD:	121506500(poglut1)

ALAT:

119015434(poglut1)

MZE:	101485624(poglut1)

ONL:	100701894 109196814

OAU:	116321027(poglut1)

OLA:	101164781(poglut1)

OML:	112160080(poglut1)

CSAI:

133425022(poglut1)

XMA:	102235605(poglut1)

XCO:	114140207(poglut1)

XHE:	116715917(poglut1)

PRET:

103476691(poglut1)

PFOR:

103156859(poglut1)

PLAI:

106935503(poglut1)

PMEI:

106930358(poglut1)

GAF:	122827302(poglut1)

PPRL:

129353787 129379065

CVG:	107086895(poglut1)

CTUL:

119790353(poglut1)

GMU:	124861651(poglut1)

NFU:	107381039(poglut1)

KMR:	108245685(poglut1)

ALIM:

106519172(poglut1)

NWH:	119428681(poglut1)

AOCE:

111566550(poglut1)

MCEP:

125000800(poglut1)

CSEM:

103389764(poglut1)

POV:	109646568(poglut1)

SSEN:

122783841(poglut1)

HHIP:

117774754(poglut1)

HSP:	118103255(poglut1)

PPLT:

128431189(poglut1)

SMAU:

118287040(poglut1)

LCF:

108900589

SDU:	111222664(poglut1)

SLAL:

111645992(poglut1)

XGL:	120797979(poglut1)

HCQ:	109510428(poglut1)

SSCV:

125988145

SBIA:

133509889(poglut1)

PEE:	133410533(poglut1)

PTAO:

133484061(poglut1)

BPEC:

110153299(poglut1)

MALB:

109955765(poglut1)

BSPL:

114848730(poglut1)

SJO:	128354190(poglut1)

SASA:

106574542(poglut1)

STRU:

115196125(poglut1)

OTW:	112266428(poglut1)

OMY:	110495774(poglut1)

OGO:	124010602(poglut1)

ONE:	115129773(poglut1)

OKI:	109879428(poglut1)

OKE:	118363831(poglut1) 118370267

SALP:

111953666(poglut1) 111971149

SNH:	120050498(poglut1)

CCLU:

121559251(poglut1)

ELS:	105019877(poglut1)

SFM:	108937696(poglut1)

PKI:	111841189(poglut1)

AANG:

118222368(poglut1)

LOC:	102682938(poglut1)

PSPA:

121320912 121327858

ARUT:

117406369 117406601

PSEX:

120522966(poglut1)

LCM:	102351249(POGLUT1)

CMK:	103190449(poglut1)

RTP:	109911835(poglut1)

CPLA:

122560311(poglut1)

HOC:	132823018(poglut1)

LERI:

129707348(poglut1)

PMRN:

116952240(POGLUT1)

LRJ:	133355521(POGLUT1) 133355555

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:

DME:	Dmel_CG31139(CG31139) Dmel_CG31152(rumi)

DER:

6554883

DSE:	6607494 6607495

DSI:	Dsimw501_GD18424(Dsim_GD18424) Dsimw501_GD18425(Dsim_GD18425)

DYA:	Dyak_GE24006

DAN:

6501062

DSR:	110177291 110177292

DPO:	4800928 6896966

DPE:	6587777 6587843

DMN:	108156655 108156657

DWI:	6646867 6646868

DGR:

6567946

DMO:	Dmoj_GI10779

DAZ:

DNV:

DHE:

CCAT:

BOD:

BDR:

RZE:	108365540 108365541 108370983

AOQ:

129241103

TDA:	119679427 119680127

MDE:	101888953 131806781

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ013394

CPII:

CNS:

BCOO:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

CSOL:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_204317

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:	113492711 113507129

SLIU:

OFU:

ATRA:

PXY:

PGW:

LGLY:

CFEL:

113370866 113370868 113371601

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:	108254559 113473964

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM609790

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_305151

DMK:	116920852 123466486

DPZ:

PVM:

PJA:

PCHN:

PMOO:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

TSP:

HRO:	HELRODRAFT_103469

LGI:	LOTGIDRAFT_225910

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:	105327429 117686636

CVN:	111105932 111106423

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LJP:

LAK:	106160124 106164609

LLON:

135491423

NVE:	116616778 5506266

EPA:

ATEN:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_18924

AQU:

100638708

CRE:	CHLRE_07g344500v5 CHLRE_08g367750v5

VCN:	VOLCADRAFT_98596

APRO:

F751_5515

CCP:	CHC_T00008884001

PNO:	SNOG_12132

PTE:

PTT_09542

BZE:	COCCADRAFT_3545

BSC:	COCSADRAFT_187637

BOR:	COCMIDRAFT_110047

AALT:

CC77DRAFT_1028215

SMIN:

v1.2.002892.t1(symbB.v1.2.002892.t1) v1.2.004773.t1(symbB.v1.2.004773.t1)

EHX:	EMIHUDRAFT_227650 EMIHUDRAFT_242134 EMIHUDRAFT_249850 EMIHUDRAFT_252748 EMIHUDRAFT_441372 EMIHUDRAFT_79465

» show all

Reference

PMID:16524674

Authors

Teng Y, Liu Q, Ma J, Liu F, Han Z, Wang Y, Wang W

Title

Cloning, expression and characterization of a novel human CAP10-like gene hCLP46 from CD34(+) stem/progenitor cells.

Journal

Gene 371:7-15 (2006)
DOI:10.1016/j.gene.2005.08.027

Sequence

[hsa:56983]

Reference

PMID:18243100

Authors

Acar M, Jafar-Nejad H, Takeuchi H, Rajan A, Ibrani D, Rana NA, Pan H, Haltiwanger RS, Bellen HJ

Title

Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling.

Journal

Cell 132:247-58 (2008)
DOI:10.1016/j.cell.2007.12.016

LinkDB

DBGET integrated database retrieval system