KEGG   ORTHOLOGY: K13941
Entry
K13941                      KO                                     
Symbol
folKP
Name
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase [EC:2.7.6.3 2.5.1.15]
Pathway
map00790  Folate biosynthesis
map01100  Metabolic pathways
map01240  Biosynthesis of cofactors
Module
M00126  Tetrahydrofolate biosynthesis, GTP => THF
M00840  Tetrahydrofolate biosynthesis, mediated by ribA and trpF, GTP => THF
M00841  Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF
Reaction
R03066  6-(hydroxymethyl)-7,8-dihydropterin:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase
R03067  (7,8-dihydropterin-6-yl)methyl diphosphate:4-aminobenzoate 2-amino-4-hydroxy-7,8-dihydropteridine-6-methenyltransferase
R03503  ATP:6-hydroxymethyl-7,8-dihydropterin 6'-diphosphotransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    K13941  folKP; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.15  dihydropteroate synthase
     K13941  folKP; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase
  2.7  Transferring phosphorus-containing groups
   2.7.6  Diphosphotransferases
    2.7.6.3  2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
     K13941  folKP; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase / dihydropteroate synthase
Other DBs
COG: COG0801 COG0294
GO: 0003848 0004156
Genes
ATH: AT1G69190 AT4G30000
ALY: 9305475 9324769
CRB: 17880032
CSAT: 104704760 104717200 104721861 104730323
EUS: EUTSA_v10019460mg EUTSA_v10024845mg
BRP: 103853027
BNA: 106390086 106450794
BOE: 106314817
RSZ: 108816768
THJ: 104821999
CPAP: 110824244
CIT: 102617876
CIC: CICLE_v10031260mg
PVY: 116132901 116132905
MINC: 123213961
TCC: 18610227
GRA: 105764458
GHI: 107934766 107946363
GAB: 108476938
HSYR: 120193436
DZI: 111318246
EGR: 104449881
GMX: 100808899
GSJ: 114387614
PVU: PHAVU_007G262100g
VRA: 106753394
VAR: 108335065
VUN: 114174130
VUM: 124819668
CCAJ: 109797823
APRC: 113868854
MTR: 11427230
TPRA: 123906113 123909635
CAM: 101493373
PSAT: 127119690
VVO: 131651746 131651753
LJA: Lj2g3v1242240.1(Lj2g3v1242240.1)
ADU: 107459818 107494290
AIP: 107604773 107612573
AHF: 112696848 112703614 112754711 112772868
LANG: 109336487 109359082
PCIN: 129322281
QSA: O6P43_025567 O6P43_032892
FVE: 101295774
RCN: 112176319
PPER: 18789267
PMUM: 103319098
PAVI: 110764830
PDUL: 117627006
MDM: 103446277
MSYL: 126607207
PXB: 103941643 103941646
ZJU: 107429058
MNT: 21409105
CSAV: 115709184
CSV: 101213228
CMO: 103496695
BHJ: 120081597
MCHA: 111018761
CMAX: 111487416
CMOS: 111447567
CPEP: 111797533
RCU: 8259548
JCU: 105649182
HBR: 110633926
MESC: 110624587
POP: 7498217
PEU: 105121755
PALZ: 118062385
JRE: 108989395
CILL: 122313206
CAVE: 132177778
QSU: 111993384
QLO: 115977225 115979054
TWL: 119990470 120002879
VVI: 100252672
VRI: 117916563
SLY: 101263512(HPPK-DHPS)
SPEN: 107018594
SOT: 102589661
SSTN: 125868319
SDUL: 129880072
CANN: 107847437
LBB: 132641945
NTA: 107768956 107807730
NSY: 104234368
NTO: 104118731
NAU: 109208294 109209500
INI: 109175260
ITR: 116002094
SIND: 105160116
OEU: 111403323
EGT: 105967515
SSPL: 121794908
SMIL: 130995945
SHIS: 125204325
APAN: 127245436
HAN: 110895339 110930934
ECAD: 122611112
LSV: 111879046
CCAV: 112527889
DCR: 108205054
CSIN: 114309557
RVL: 131301039
AEW: 130778929 130779906
BVG: 104895769
SOE: 110785434
CQI: 110721688
ATRI: 130808519 130809374
MOF: 131154253
NNU: 104590292 104598169
MING: 122057234 122094169
TSS: 122664765
PSOM: 113281838
DOSA: Os07t0618500-01(Os07g0618500)
OGL: 127780010
BDI: 100844418
ATS: 109744625
TDC: 119353780 119362965
TAES: 100049049 123044194
TUA: 125536221
LPER: 127296731 127332661
LRD: 124670633 124670658
SBI: 8060337
ZMA: 100280079
SITA: 101770243 101784334
SVS: 117833469 117856136
PVIR: 120673770 120694498 120694499
PHAI: 112895187
PDA: 103697287
EGU: 105057066
MUS: 103997371
ZOF: 122008414 122016031
DCT: 110102673
PEQ: 110026526
AOF: 109844581 109846435
MSIN: 131219400
NCOL: 116259367
ATR: 18446233
SMO: SELMODRAFT_102265 SELMODRAFT_80180
PPP: 112278223
CSL: COCSUDRAFT_14477
CVR: CHLNCDRAFT_28666
APRO: F751_3687
OLU: OSTLU_2171
OTA: OT_ostta06g02900
BPG: Bathy05g03140
MIS: MICPUN_55706
MPP: MICPUCDRAFT_51589(JGI:MicpuC2_51589)
CME: CYME_CMQ278C
GSL: Gasu_52790
CCP: CHC_T00007059001
NCR: NCU09930
NTE: NEUTE1DRAFT80286(NEUTE1DRAFT_80286)
SMP: SMAC_01662
PAN: PODANSg3603
PBEL: QC761_122520(FOL1)
PPSD: QC762_122520(FOL1)
PPSP: QC763_122520(FOL1)
PPSA: QC764_122520(FOL1)
TTT: THITE_2122567
MTM: MYCTH_2068493
CTHR: CTHT_0038640
MGR: MGG_01474
PPEI: PpBr36_00988
PGRI: PgNI_04036
TMN: UCRPA7_1388
SSCK: SPSK_00484
FGR: FGSG_09710
FPU: FPSE_04316
FPOA: FPOAC1_011934
FVN: FVRRES_13002
FVR: FVEG_06316
FOX: FOXG_08357
NHE: NECHADRAFT_32861
FFC: NCS54_00255100
FKR: NCS57_00250500
FMU: J7337_004470
TRE: TRIREDRAFT_56002
TRR: M419DRAFT_5799
MAW: MAC_08429
MAJ: MAA_06440
PCHM: VFPPC_13782
CMT: CCM_04032
AMUS: LMH87_006631
PLJ: VFPFJ_01061
PTKZ: JDV02_007604(FOL1)
VAL: VDBG_00979
VDA: VDAG_00591
CFJ: CFIO01_12648
CLUP: CLUP02_17543
CHIG: CH63R_07826
SAPO: SAPIO_CDS8367
ELA: UCREL1_2769
PFY: PFICI_05162
SSL: SS1G_14464
BFU: BCIN_15g05100(Bcfol1)
MBE: MBM_06552
PSCO: LY89DRAFT_656218
GLZ: GLAREA_04002
ANI: ANIA_06032
AFM: AFUA_2G09840
ACT: ACLA_068920
NFI: NFIA_085290
AOR: AO090011000651
ANG: An16g05350
ALUC: AKAW2_70447S(FOL1)
ACHE: ACHE_40958A(FOL1)
APUU: APUU_11121S(FOL1)
PCS: N7525_004398
PDP: PDIP_64980
POU: POX_f07876
TMF: EYB26_004757
TRG: TRUGW13939_01886
CIM: CIMG_07826
CPW: CPC735_041780
URE: UREG_02157
PBL: PAAG_01324
PBN: PADG_00443
ABE: ARB_05172
TVE: TRV_03584
AJE: HCAG_08187
BGH: BDBG_06984
PNO: SNOG_13596
PTE: PTT_18425
BZE: COCCADRAFT_34117
BSC: COCSADRAFT_36070
BOR: COCMIDRAFT_38902
AALT: CC77DRAFT_983298
ARAB: EKO05_0011032
ZTR: MYCGRDRAFT_41254
PFJ: MYCFIDRAFT_143607
NPA: UCRNP2_4867
LBC: LACBIDRAFT_247939
MPR: MPER_06832
WSE: WALSEDRAFT_15711
MGL: MGL_1723
PGR: PGTG_05359 PGTG_12640
PTRC: PtA15_3A441
PSTR: Pst134EA_007376 Pst134EA_007382
MLR: MELLADRAFT_90514 MELLADRAFT_93610
PFA: PF3D7_0810800
PFH: PFHG_02567
PREI: PRSY57_0810100
PGAB: PGSY75_0810800
PYO: PY17X_1428800
PCB: PCHAS_1428500
PBE: PBANKA_1426700
PVV: PVVCY_1402860
PKN: PKNH_1429900
PVX: PVX_123230
PCY: PCYB_143740
PMAL: PMUG01_14045500(PPPK-DHPS)
PREL: PRELSG_1426800(DHPS)
TGO: TGME49_259550
PTI: PHATRDRAFT_12107
TPS: THAPSDRAFT_37471(DPS1)
AAF: AURANDRAFT_20752
PIF: PITG_08129
PSOJ: PHYSODRAFT_565841
SPAR: SPRG_19504
EHX: EMIHUDRAFT_215177 EMIHUDRAFT_234285 EMIHUDRAFT_235458
GTT: GUITHDRAFT_157785
RVI: RVIR1_03670(folKP)
ALG: AQULUS_20280(folP)
ASIP: AQUSIP_00040(folP)
FTU: FTT_0942c(folK)
FTQ: RO31_1082(folK)
FTF: FTF0942c(folK)
FTW: FTW_0836
FTR: NE061598_05395
FTT: FTV_0896(folK)
FTG: FTU_0980(folK)
FTL: FTL_1265
FTH: FTH_1240(folK_folP)
FTA: FTA_1338(folK)
FTS: F92_07020
FTI: FTS_1237(folK)
FTO: X557_06580
FTC: DA46_1508(folK)
FTV: CH67_1639(folK)
FTZ: CH68_1370(folK)
FTM: FTM_1008
FTN: FTN_0819
FTX: AW25_1200(folK)
FTD: AS84_1721(folK)
FTY: CH70_1203(folK)
FCF: FNFX1_0828
FCN: FN3523_0966
FHI: FSC454_05230
FPH: Fphi_1795
FPT: BZ13_193(folK)
FPI: BF30_51(folK)
FPM: LA56_378(folK)
FPX: KU46_1500(folK)
FPZ: LA55_987(folK)
FPJ: LA02_1493(folK)
FRT: F7308_1321
FNA: OOM_1500
FNL: M973_05250
FRF: LO80_01275
FHA: CDV26_07645(folK)
FRX: F7310_05090
FRM: BBG19_0843
FRC: KX01_1304(folK)
FAD: CDH04_04945
FMI: F0R74_03525(folP)
FOO: CGC45_04280(folK)
FNN: FSC774_02620(folP)
FSR: KQR59_05095(folP)
FRL: FIP56_05215(folP)
FGU: SD28_04420
AFRI: E3E15_04050(folP)
AII: E4K63_04320(folP)
CYS: NYP54_10655(folP)
RBE: RBE_0032(folKP)
RBO: A1I_00170
RCO: RC0037
RFE: RF_0039(folKP)
RRI: A1G_00225
RRA: RPO_00220
RRC: RPL_00220
RRH: RPM_00225
RRB: RPN_06665
RRN: RPJ_00225
RRM: RRM_00245
RRR: RRR_00245
RMO: MCI_04355
RMC: RMONA_01675(folP)
RAS: RAS_00510
RTL: H6P87_00040
RKT: FLA4_04520
MENM: LF888_03255(folP)
WOL: WD_0883
WRI: WRi_008620(folKP)
WEN: wHa_07640(folP)
WED: wNo_03610(folKP)
WOO: wOo_06880
WCL: WCLE_011740(folKP)
WPP: DEJ70_01000
WEC: wCauA_06680(folP)
WDM: EJB00_05465(folP)
WEA: EA652_0861(folK)
WEY: wYak_06040(folKP)
WET: GOY13_01660(folP)
WEW: HUB92_05000(folP)
WER: wSan_06040(folKP)
WEF: GOY12_01380(folP)
WEP: JSQ73_003620(folP)
WEH: J4T77_04450(folP)
WEE: LOK48_04165(folP)
WEG: L0Z57_04380(folK) L0Z57_04385(folP)
WEU: GOY14_01420(folP)
WEJ: L2227_05185(folP)
SSIV: MJ631_06945(folP)
WEX: M1L25_000877(folP)
WEK: M1L26_000883(folP)
WEQ: NHG98_00465(folP)
WEV: ONI09_01770(folP)
WEND: M3L71_01580(folP)
WEDC: R0F62_03045(folP)
WEZT: R0F63_01190(folP)
WELO: NMD99_07535(folP)
FSO: Fsol_00743
RBT: NOVO_03610(folP)
EAA: I862_07140
LNE: FZC33_31645(folP)
BDQ: CIK05_03665
BEX: A11Q_798
PSUB: Pelsub_P0042
THUG: KNN16_06735(folP)
CTR: CT_613(folP)
CTD: CTDEC_0613(folP)
CTF: CTDLC_0613(folP)
CTRD: SOTOND1_00651
CTRO: SOTOND5_00649
CTRT: SOTOND6_00649
CTA: CTA_0666(folP)
CTY: CTR_6171(folP)
CRA: CTO_0666
CTRQ: A363_00658
CTRX: A5291_00657
CTRZ: A7249_00656
CTRP: L11322_00644
CTLJ: L1115_00644
CTLX: L1224_00644
CTLL: L1440_00647
CTB: CTL0877(folP)
CTRR: L225667R_00646
CTLF: CTLFINAL_04580
CTLI: CTLINITIAL_04575
CTL: CTLon_0871(folP)
CTRU: L2BUCH2_00643
CTRL: L2BLST_00643
CTRV: L2BCV204_00643
CTRM: L2BAMS1_00643
CTLA: L2BAMS2_00643
CTLM: L2BAMS3_00643
CTLS: L2BAMS4_00644
CTLZ: L2BAMS5_00644
CTLC: L2BCAN1_00644
CTLN: L2BCAN2_00644
CTLB: L2B795_00644
CTLQ: L2B8200_00643
CTO: CTL2C_439(folP)
CTRN: L3404_00644
CTJ: JALI_6171(folP)
CTZ: CTB_6171(folP)
CTG: E11023_03220
CTK: E150_03240
CSW: SW2_6241(folP)
CES: ESW3_6241(folP)
CTRB: BOUR_00653
CTRE: SOTONE4_00648
CTRS: SOTONE8_00654
CTEC: EC599_6351(folP)
CFS: FSW4_6241(folP)
CFW: FSW5_6241(folP)
CTFW: SWFP_6621(folP)
CTRF: SOTONF3_00648
CTCH: O173_03365
CTN: G11074_03220
CTQ: G11222_03240
CTV: CTG9301_03235
CTW: G9768_03220
CTRG: SOTONG1_00649
CTRI: BN197_6221(folP)
CTRA: BN442_6221(folP)
CTRH: SOTONIA1_00652
CTRJ: SOTONIA3_00652
CTRK: SOTONK1_00649
CTJT: CTJTET1_03260
CTCF: CTRC69_03250
CTFS: CTRC342_03275
CTHF: CTRC852_03285
CTCJ: CTRC943_03220
CTHJ: CTRC953_03220
CTMJ: CTRC966_03230
CTTJ: CTRC971_03240
CTJS: CTRC122_03265
CTRC: CTRC55_03230
CTRW: CTRC3_03260
CTRY: CTRC46_03235
CTCT: CTW3_03380
CMU: TC_0903(folK_P)
CMUR: Y015_04785
CMN: BB17_04840
CMM: NC80_04560
CMG: NC81_04580
CMX: DNC_04590
CMZ: TAC_04785
CPN: CPn_0758(folP)
CPA: CP_1114
CPJ: folP(folP)
CPT: CpB0786
CLP: CPK_ORF00164(folKP)
CHP: CPSIT_1059(folKP)
CHB: G5O_1051
CHS: CPS0A_1082(folK)
CHI: CPS0B_1067(folK)
CHT: CPS0D_1077(folK)
CHC: CPS0C_1077(folK)
CHR: Cpsi_9851(folKP)
CPSC: B711_1141(folP)
CPSN: B712_1071(folK)
CPSB: B595_1146(folK)
CPSG: B598_1070(folK)
CPSM: B602_1074(folK)
CPSI: B599_1068(folK)
CPSV: B600_1141(folK)
CPSW: B603_1077(folK)
CPST: B601_1076(folK)
CPSD: BN356_9891(folKP)
CPSA: AO9_05135
CAV: M832_07850(folKP)
CCA: CCA_00999(folKP)
CAB: CAB969(folKP)
CABO: AB7_10651(folKP)
CFE: CF0014(folP)
CGZ: M787_001840
CHLA: C834K_1029(folP)
CSUI: Chls_966(folP)
CBUE: HBN95_00540(folP)
CSEE: C10C_0729(folP)
CCRD: H9Q19_02325(folP)
CPAA: FI836_02620(folP)
 » show all
Reference
PMID:17289662
  Authors
Storozhenko S, Navarrete O, Ravanel S, De Brouwer V, Chaerle P, Zhang GF, Bastien O, Lambert W, Rebeille F, Van Der Straeten D
  Title
Cytosolic hydroxymethyldihydropterin pyrophosphokinase/dihydropteroate synthase from Arabidopsis thaliana: a specific role in early development and stress response.
  Journal
J Biol Chem 282:10749-61 (2007)
DOI:10.1074/jbc.M701158200
  Sequence
[ath:AT1G69190 AT4G30000]
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