KEGG ORTHOLOGY: K13997

ORTHOLOGY: K13997

Entry

K13997                      KO

Symbol

PDHX

Name

dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex

Pathway

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map01120

Microbial metabolism in diverse environments

Module

M00307

Pyruvate oxidation, pyruvate => acetyl-CoA

Disease

H00072

Pyruvate dehydrogenase complex deficiency

H02003

Pyruvate dehydrogenase E3-binding protein deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    K13997  PDHX; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
   00020 Citrate cycle (TCA cycle)
    K13997  PDHX; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
   00620 Pyruvate metabolism
    K13997  PDHX; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
  09112 Not included in regular maps
   09113 Global maps only
    K13997  PDHX; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex

Genes

HSA:	8050(PDHX)

PTR:	451120(PDHX)

PPS:	100991366(PDHX)

GGO:	101137782(PDHX)

PON:	100455315(PDHX)

NLE:	100586539(PDHX)

HMH:	116476358(PDHX)

MCC:	717932(PDHX)

MCF:	101866848(PDHX)

MTHB:

126936309

MNI:	105471551(PDHX)

CSAB:

103237844(PDHX)

CATY:

105586796(PDHX)

PANU:

101010791(PDHX)

TGE:	112606013(PDHX)

MLEU:

105528694(PDHX)

RRO:	104658353(PDHX)

RBB:	108513827(PDHX)

TFN:	117081593(PDHX)

PTEH:

111521861(PDHX)

CANG:

105510792(PDHX)

CJC:	100408808(PDHX)

SBQ:	101027781(PDHX)

CIMI:

108305766(PDHX)

CSYR:

103258732(PDHX)

MMUR:

105866202(PDHX)

LCAT:

123642587(PDHX)

PCOQ:

105814540(PDHX)

OGA:	100943591(PDHX)

MMU:	27402(Pdhx)

MCAL:

110285583(Pdhx)

MPAH:

110318254(Pdhx)

MCOC:

116090565(Pdhx)

ANU:	117703476(Pdhx)

MUN:	110560531(Pdhx)

CGE:	100750352(Pdhx)

MAUA:

101825621(Pdhx)

PROB:

127222177(Pdhx)

PLEU:

114699008(Pdhx)

MORG:

121465881(Pdhx)

MFOT:

126504646

AAMP:

119815482(Pdhx)

NGI:	103749500(Pdhx)

HGL:	101703743(Pdhx)

CPOC:

100732258(Pdhx)

CCAN:

109699234(Pdhx)

DORD:

105988135(Pdhx)

DSP:	122117698(Pdhx)

PLOP:

125362665(Pdhx)

NCAR:

124959746

MMMA:

107135753(Pdhx)

OCU:

100349815

OPI:	101533333(PDHX)

TUP:	102489034(PDHX)

GVR:	103589776(PDHX)

CFA:	475942(PDHX)

CLUD:

112663461(PDHX)

VVP:	112930438(PDHX)

VLG:	121472198(PDHX)

NPO:	129494140(PDHX)

AML:	100475970(PDHX)

UMR:	103659320(PDHX)

UAH:	113265044(PDHX)

UAR:	123799424(PDHX)

ELK:

111150192

LLV:

125078500

MPUF:

101685299(PDHX)

MNP:	132021467(PDHX)

MLK:	131811254(PDHX)

NVS:	122912836(PDHX)

ORO:	101371115(PDHX)

EJU:	114196935(PDHX)

ZCA:	113913967(PDHX)

MLX:	118015757(PDHX)

NSU:	110576270(PDHX)

LWW:	102738982(PDHX)

FCA:	101095373(PDHX)

PYU:	121043554(PDHX)

PCOO:

112865023(PDHX)

PBG:	122483697(PDHX)

PVIV:

125176382(PDHX)

LRUF:

124505719

PTG:	102957491(PDHX)

PPAD:

109279173(PDHX)

PUC:

125934778

AJU:

106976923

HHV:	120232562(PDHX)

BTA:	517402(PDHX)

BOM:	102282245(PDHX)

BIU:	109569726(PDHX)

BBUB:

102407043(PDHX)

BBIS:

104982467(PDHX)

CHX:	102171631(PDHX)

OAS:	101105774(PDHX)

BTAX:

128060177(PDHX)

ODA:	120876874(PDHX)

CCAD:

122449584(PDHX)

MBEZ:

129554752(PDHX)

SSC:	100525559(PDHX)

CFR:	102522291(PDHX)

CBAI:

105076512(PDHX)

CDK:	105106810(PDHX)

VPC:	102543170(PDHX)

BACU:

103012403

BMUS:

118899042(PDHX)

LVE:

103070404

OOR:	101274152(PDHX)

DLE:	111179782(PDHX)

PCAD:

102978577(PDHX)

PSIU:

116758214(PDHX)

NASI:

112404576(PDHX)

ECB:	100059260(PDHX)

EPZ:	103564240(PDHX)

EAI:	106837492(PDHX)

MYB:	102251297(PDHX)

MYD:	102767363(PDHX)

MMYO:

118665144(PDHX)

MLF:	102424846(PDHX)

PKL:	118713640(PDHX)

EFUS:

103290880(PDHX)

MNA:	107531979(PDHX)

DRO:	112303270(PDHX)

SHON:

118983167(PDHX)

AJM:	119036462(PDHX)

PDIC:

114499365(PDHX)

PHAS:

123810086(PDHX)

MMF:	118628338(PDHX)

PPAM:

129080466(PDHX)

HAI:	109381149(PDHX)

RFQ:	117031169(PDHX)

PALE:

102884809(PDHX)

PGIG:

120605805(PDHX)

PVP:	105289973(PDHX)

RAY:	107504103(PDHX)

MJV:	108395360(PDHX)

TOD:	119255366(PDHX)

SARA:

101543817(PDHX)

SETR:

126017926(PDHX)

LAV:	100660107(PDHX)

TMU:

101341288

ETF:	101655054(PDHX)

DNM:	101423184(PDHX)

MDO:	100031583(PDHX)

GAS:	123253118(PDHX)

SHR:	100929357(PDHX)

AFZ:

127541133

PCW:	110192599(PDHX)

OAA:	100076542(PDHX)

GGA:	423154(PDHX)

PCOC:

116229106(PDHX)

MGP:	100544023(PDHX)

CJO:	107314394(PDHX)

TPAI:

128086531(PDHX)

LMUT:

125695438(PDHX)

NMEL:

110401235(PDHX)

APLA:

101803414(PDHX)

ACYG:

106044475(PDHX)

CATA:

118250769(PDHX)

AFUL:

116489700(PDHX)

TGU:	100220979(PDHX)

LSR:	110484458(PDHX)

SCAN:

103826729(PDHX)

PMOA:

120511386(PDHX)

OTC:	121344838(PDHX)

PRUF:

121360936(PDHX)

GFR:	102042180(PDHX)

FAB:	101808793(PDHX)

OMA:	130253661(PDHX)

PHI:	102103793(PDHX)

PMAJ:

107205796(PDHX)

CCAE:

111930062(PDHX)

CCW:	104688045(PDHX)

CBRC:

103620908(PDHX)

ETL:	114056741(PDHX)

ZAB:	102067168(PDHX)

SVG:	106851522(PDHX)

MMEA:

130584281(PDHX)

HRT:	120753821(PDHX)

FPG:	101910899(PDHX)

FCH:	102059751(PDHX)

CLV:	102097567(PDHX)

EGZ:	104134091(PDHX)

NNI:	104011737(PDHX)

PLET:

104619108(PDHX)

EHS:	104516762(PDHX)

PCAO:

104048691

ACUN:

113481162(PDHX)

TALA:

104367571(PDHX)

PADL:

103917522(PDHX)

AFOR:

103894312(PDHX)

ACHC:

115350362(PDHX)

HLE:	104843221(PDHX)

AGEN:

126049176

GCL:

127016788

CMAC:

104483140(PDHX)

MUI:	104534143(PDHX)

BREG:

104636152(PDHX)

GSTE:

104254046(PDHX)

LDI:	104343736(PDHX)

MNB:	103778027(PDHX)

OHA:	104330083(PDHX)

NNT:

104400132

SHAB:

115606249(PDHX)

DPUB:

104302566(PDHX)

ACAR:

104521492(PDHX)

CPEA:

104388419(PDHX)

AVIT:

104277220(PDHX)

CVF:	104287716(PDHX)

RTD:	128909436(PDHX)

CUCA:

104068991(PDHX)

BRHI:

104491559(PDHX)

AAM:	106498128(PDHX)

AROW:

112977232(PDHX)

NPD:	112943498(PDHX)

TGT:	104577692(PDHX)

DNE:	112983100(PDHX)

SCAM:

104152872(PDHX)

ASN:	102371772(PDHX)

AMJ:	102577342(PDHX)

CPOO:

109321380(PDHX)

GGN:	109298961(PDHX)

PSS:	102460348(PDHX)

CMY:	102939091(PDHX)

CCAY:

125639113(PDHX)

DCC:	119857036(PDHX)

CPIC:

101935014(PDHX)

TST:	117877011(PDHX)

CABI:

116819164(PDHX)

MRV:	120405120(PDHX)

ACS:

100556411

ASAO:

132768696(PDHX)

PVT:	110073524(PDHX)

SUND:

121934465(PDHX)

PBI:	103067916(PDHX)

PMUR:

107290424(PDHX)

CTIG:

120314116(PDHX)

TSR:	106556939(PDHX)

PGUT:

117665461(PDHX)

APRI:

131187413(PDHX)

PTEX:

113440629(PDHX)

NSS:	113410238(PDHX)

VKO:	123026713(PDHX)

PMUA:

114596487(PDHX)

PRAF:

128413751(PDHX)

ZVI:	118085585(PDHX)

HCG:	128328512(PDHX)

GJA:	107109630(PDHX)

STOW:

125426331(PDHX)

EMC:	129324143(PDHX)

XLA:	108715255(pdhx.S) 447247(pdhx.L)

XTR:	100379696(pdhx)

NPR:	108787818(PDHX)

RTEM:

120917076(PDHX)

BBUF:

120980561(PDHX)

BGAR:

122920182(PDHX)

MUO:	115468792(PDHX)

GSH:	117352091(PDHX)

DRE:	393532(pdhx)

SRX:	107748940(pdhx)

SANH:

107695430(pdhx)

SGH:	107566832(pdhx)

CCAR:

109064662(pdhx)

CAUA:

113067162(pdhx)

CGIB:

127947398

PTET:

122341140(pdhx)

LROH:

127161976(pdhx)

OMC:	131534216(pdhx)

PPRM:

120478373(pdhx)

RKG:	130083245(pdhx)

MAMB:

125247253(pdhx)

CIDE:

127506986

MASI:

127435771

TROS:

130550963(pdhx)

TDW:	130414510(pdhx)

MANU:

129434909(pdhx) 129434910

IPU:

108275063

IFU:	128617956(pdhx)

PHYP:

113529836(pdhx)

SMEO:

124392678(pdhx)

TFD:	113660131(pdhx)

TVC:	132857024(pdhx)

TRN:	134320299(pdhx)

AMEX:

103021725(pdhx)

CMAO:

118811593(pdhx)

EEE:	113568089(pdhx)

CHAR:

105900743(pdhx)

TRU:	101070208(pdhx)

TFS:	130535727(pdhx)

TNG:	GSTEN00021477G001

LCO:	104920483(pdhx)

NCC:	104963724(pdhx)

TBEN:

117491595(pdhx)

CGOB:

115010170(pdhx)

PGEO:

117448395(pdhx)

GACU:

117545928(pdhx)

EMAC:

134859443(pdhx)

ELY:	117261661(pdhx)

EFO:	125887594(pdhx)

PLEP:

121950798(pdhx)

SLUC:

116038676(pdhx)

ECRA:

117949697(pdhx)

ESP:	116694765(pdhx)

PFLV:

114560743(pdhx)

GAT:	120809398(pdhx)

PPUG:

119196304(pdhx)

AFB:	129108333(pdhx)

CLUM:

117732499(pdhx)

PSWI:

130194865(pdhx)

MSAM:

119893818(pdhx)

SCHU:

122875061(pdhx)

CUD:	121514533(pdhx)

ALAT:

119024841(pdhx)

MZE:	101479848(pdhx)

ONL:	100708056(pdhx)

OAU:	116311499(pdhx)

OLA:	101170510(pdhx)

OML:	112152819(pdhx)

CSAI:

133444052(pdhx)

XMA:	102217095(pdhx)

XCO:	114133464(pdhx)

XHE:	116708752(pdhx)

PRET:

103466130(pdhx)

PFOR:

103133646(pdhx)

PLAI:

106936421(pdhx)

PMEI:

106929222(pdhx)

GAF:	122835567(pdhx)

PPRL:

129365886(pdhx)

CVG:	107085410(pdhx)

CTUL:

119776701(pdhx)

GMU:	124856146(pdhx)

NFU:	107388987(pdhx)

KMR:	108239920(pdhx)

ALIM:

106515637(pdhx)

NWH:	119416002(pdhx)

AOCE:

111563941(pdhx)

MCEP:

125015174(pdhX)

CSEM:

103380507(pdhx)

POV:	109624630(pdhx)

SSEN:

122776300(pdhx)

HHIP:

117763481(pdhx)

HSP:	118109762(pdhx)

PPLT:

128445009(pdhx)

SMAU:

118315600(pdhx)

LCF:

108875251

SDU:	111228736(pdhx)

SLAL:

111671251(pdhx)

XGL:	120793648(pdhx)

HCQ:	109530475(pdhx)

SSCV:

125970206

SBIA:

133502172(pdhx)

PEE:	133403084(pdhx)

PTAO:

133477871(pdhx)

BPEC:

110169386(pdhx)

MALB:

109968740(pdhx)

BSPL:

114857704(pdhx)

SJO:	128359095(pdhx)

SASA:

106573349(pdhx)

STRU:

115152127(pdhx)

OTW:	112252514(pdhx)

OMY:	110502133 110522340(pdhx)

OGO:	124002167(pdhx) 124041394

ONE:	115109518(pdhx)

OKI:	109866983 109889491(pdhx)

OKE:	118401136(pdhx)

SALP:

111952503(pdhx)

SNH:	120054026(pdhx)

CCLU:

121576402(pdhx)

ELS:	105005992(pdhx)

SFM:	108942440(pdhx)

PKI:	111859492(pdhx)

AANG:

118215334(pdhx)

LOC:	102682612(pdhx)

PSPA:

121294769(pdhx)

ARUT:

117432403 117435071

PSEX:

120523063(pdhx)

LCM:	102348671(PDHX)

CMK:	103190636(pdhx)

CPLA:

122557970(pdhx)

HOC:	132824144(pdhx)

LERI:

129705888(pdhx)

BFO:

BBEL:

CIN:

SPU:

LPIC:

APLC:

AJC:

SKO:

CSOL:

SGRE:

IEL:

FCD:

DPX:	DAPPUDRAFT_299977

DMK:

DPZ:

PCHN:

HAME:

PCLA:

CQD:

PTRU:

ESN:	127003492 127003512

HAZT:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

RPHI:

DPOL:

LAK:

SMM:	Smp_066410

OVI:	T265_00275

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

TAD:	TRIADDRAFT_61347

AQU:

100634770

SPAR:

SPRG_19552

NGR:	NAEGRDRAFT_78558

» show all

Reference

PMID:9242632

Authors

Harris RA, Bowker-Kinley MM, Wu P, Jeng J, Popov KM

Title

Dihydrolipoamide dehydrogenase-binding protein of the human pyruvate dehydrogenase complex. DNA-derived amino acid sequence, expression, and reconstitution of the pyruvate dehydrogenase complex.

Journal

J Biol Chem 272:19746-51 (1997)
DOI:10.1074/jbc.272.32.19746

Sequence

[hsa:8050]

LinkDB

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