KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00904 Diterpenoid biosynthesis
K14039 E1.14.14.176; taxadiene 5alpha-hydroxylase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.176 taxadiene 5alpha-hydroxylase
K14039 E1.14.14.176; taxadiene 5alpha-hydroxylase
Hefner J, Rubenstein SM, Ketchum RE, Gibson DM, Williams RM, Croteau R
Title
Cytochrome P450-catalyzed hydroxylation of taxa-4(5),11(12)-diene to taxa-4(20),11(12)-dien-5alpha-ol: the first oxygenation step in taxol biosynthesis.