KEGG   ORTHOLOGY: K14042
Entry
K14042            Tight     KO                                     
Symbol
TPS-ISO
Name
isopimara-7,15-diene synthase /copalyl diphosphate synthase [EC:4.2.3.44 5.5.1.12]
Pathway
map00904  Diterpenoid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R06298  (+)-copalyl-diphosphate lyase (decyclizing)
R09111  (+)-copalyl diphosphate-lyase (isopimara-7,15-diene-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00904 Diterpenoid biosynthesis
    K14042  TPS-ISO; isopimara-7,15-diene synthase /copalyl diphosphate synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.3  Acting on phosphates
    4.2.3.44  isopimara-7,15-diene synthase
     K14042  TPS-ISO; isopimara-7,15-diene synthase /copalyl diphosphate synthase
 5. Isomerases
  5.5  Intramolecular lyases
   5.5.1  Intramolecular lyases (only sub-subclass identified to date)
    5.5.1.12  copalyl diphosphate synthase
     K14042  TPS-ISO; isopimara-7,15-diene synthase /copalyl diphosphate synthase
Other DBs
GO: 0050559
Genes
AG: AAS47690(TPS-ISO)
Reference
  Authors
Martin DM, Faldt J, Bohlmann J
  Title
Functional characterization of nine Norway Spruce TPS genes and evolution of gymnosperm terpene synthases of the TPS-d subfamily.
  Journal
Plant Physiol 135:1908-27 (2004)
DOI:10.1104/pp.104.042028
  Sequence
Reference
  Authors
Wilderman PR, Peters RJ
  Title
A single residue switch converts abietadiene synthase into a pimaradiene specific cyclase.
  Journal
J Am Chem Soc 129:15736-7 (2007)
DOI:10.1021/ja074977g
LinkDB

DBGET integrated database retrieval system