| Entry |
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| Symbol |
aveA1
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| Name |
avermectin polyketide synthase AveA1
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| Pathway |
| map00522 | Biosynthesis of 12-, 14- and 16-membered macrolides |
| map01110 | Biosynthesis of secondary metabolites |
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| Module |
| M00777 | Avermectin biosynthesis, 2-methylbutanoyl-CoA/isobutyryl-CoA => 6,8a-Seco-6,8a-deoxy-5-oxoavermectin 1a/1b aglycone => avermectin A1a/B1a/A1b/B1b |
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| Reaction |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
K14371 aveA1; avermectin polyketide synthase AveA1
00522 Biosynthesis of 12-, 14- and 16-membered macrolides
K14371 aveA1; avermectin polyketide synthase AveA1
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K14371 aveA1; avermectin polyketide synthase AveA1
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide synthase (PKS)
Modular type I PKS
cis-AT PKS
Avermectin PKS
K14371 aveA1; avermectin polyketide synthase AveA1
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| Genes |
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| Reference |
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| Authors |
Ikeda H, Nonomiya T, Omura S |
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| Title |
Organization of biosynthetic gene cluster for avermectin in Streptomyces avermitilis: analysis of enzymatic domains in four polyketide synthases. |
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| Journal |
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| Reference |
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| Authors |
Ikeda H, Nonomiya T, Usami M, Ohta T, Omura S |
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| Title |
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis. |
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| Journal |
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| Sequence |
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| LinkDB |
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