KEGG ORTHOLOGY: K14469

ORTHOLOGY: K14469

Entry

K14469                      KO

Symbol

K14469

Name

acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase [EC:1.3.1.84 4.2.1.116 6.2.1.36]

Pathway

map00720

Carbon fixation pathways in prokaryotes

map01100

Metabolic pathways

map01120

Microbial metabolism in diverse environments

map01200

Carbon metabolism

Module

M00376

3-Hydroxypropionate bi-cycle

Reaction

R00919

propanoyl-CoA:NADP+ 2-oxidoreductase

R03045

3-hydroxypropionyl-CoA hydro-lyase

R09286

3-hydroxypropionate:CoA ligase (AMP-forming)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09102 Energy metabolism
   00720 Carbon fixation pathways in prokaryotes
    K14469  K14469; acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.84  acrylyl-CoA reductase (NADPH)
     K14469  K14469; acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase
4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.116  3-hydroxypropionyl-CoA dehydratase
     K14469  K14469; acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase
6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.36  3-hydroxypropionyl-CoA synthase
     K14469  K14469; acrylyl-CoA reductase (NADPH) / 3-hydroxypropionyl-CoA dehydratase / 3-hydroxypropionyl-CoA synthetase

Other DBs

GO:	0043957 0043956 0043955

Genes

HJA:	BST95_10575

PAQM:

E0F26_07705

SRAD:

LLW23_04770

BLAS:

BSY18_2664

BFW:	B5J99_04275

PALG:

HFP57_16695

SAND:

H3309_14800

POQ:	KZX46_11635

PMEA:

KTC28_17240

ELQ:	Ga0102493_111749

ERK:	CD351_07815

PNS:	A9D12_09050

PORL:

BG023_111318

PHZ:	CHX26_07195

POT:	E2E27_15415

ABS:	AZOBR_160075

ABQ:	ABAZ39_03340

ABF:	AMK58_10665

AZT:	TSH58p_14860

AZZ:	DEW08_10205

AARE:

D3093_05870

ASOC:

CB4_03834(acs)

RRS:	RoseRS_3202

RCA:

Rcas_2930

CAU:

Caur_0613

CHL:	Chy400_0662

CAG:

Cagg_3394

CTM:	Cabther_B0610

CVL:	J8C06_12460

CHLO:

J8C02_11660

GGR:	HKW67_05055

CTS:

Ctha_1050

HAKZ:

J0X25_09315

NAY:	HYG81_22555

NOU:	Natoc_3706

NARA:

QQ977_05470

» show all

Reference

PMID:19955419

Authors

Zarzycki J, Brecht V, Muller M, Fuchs G

Title

Identifying the missing steps of the autotrophic 3-hydroxypropionate CO2 fixation cycle in Chloroflexus aurantiacus.

Journal

Proc Natl Acad Sci U S A 106:21317-22 (2009)
DOI:10.1073/pnas.0908356106

Reference

PMID:11821399

Authors

Alber BE, Fuchs G

Title

Propionyl-coenzyme A synthase from Chloroflexus aurantiacus, a key enzyme of the 3-hydroxypropionate cycle for autotrophic CO2 fixation.

Journal

J Biol Chem 277:12137-43 (2002)
DOI:10.1074/jbc.M110802200

Sequence

[chl:Chy400_0662]

LinkDB

DBGET integrated database retrieval system