KEGG   ORTHOLOGY: K14655
Entry
K14655                      KO                                     
Symbol
RIB2, PUS8
Name
tRNA pseudouridine32 synthase / 2,5-diamino-6-(5-phospho-D-ribitylamino)-pyrimidin-4(3H)-one deaminase [EC:5.4.99.28]
Pathway
map00740  Riboflavin metabolism
map01100  Metabolic pathways
map01240  Biosynthesis of cofactors
Module
M00911  Riboflavin biosynthesis, fungi, GTP => riboflavin/FMN/FAD
Reaction
R09377  2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one 2-aminohydrolase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00740 Riboflavin metabolism
    K14655  RIB2, PUS8; tRNA pseudouridine32 synthase / 2,5-diamino-6-(5-phospho-D-ribitylamino)-pyrimidin-4(3H)-one deaminase
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis
    K14655  RIB2, PUS8; tRNA pseudouridine32 synthase / 2,5-diamino-6-(5-phospho-D-ribitylamino)-pyrimidin-4(3H)-one deaminase
Enzymes [BR:ko01000]
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.99  Transferring other groups
    5.4.99.28  tRNA pseudouridine32 synthase
     K14655  RIB2, PUS8; tRNA pseudouridine32 synthase / 2,5-diamino-6-(5-phospho-D-ribitylamino)-pyrimidin-4(3H)-one deaminase
Transfer RNA biogenesis [BR:ko03016]
 Eukaryotic type
  tRNA modification factors
   Psudouridine synthases
    K14655  RIB2, PUS8; tRNA pseudouridine32 synthase / 2,5-diamino-6-(5-phospho-D-ribitylamino)-pyrimidin-4(3H)-one deaminase
Other DBs
COG: COG0564 COG0117
GO: 0009982 0043723
Genes
SCE: YOL066C(RIB2)
SEUB: DI49_2338
SPAO: SPAR_O00860
AGO: AGOS_AEL091C
ERC: Ecym_3555
KLA: KLLA0_F24794g
KMX: KLMA_60282(RIB2)
LTH: KLTH0C08756g
VPO: Kpol_1032p14
ZRO: ZYRO0B05082g
NCS: NCAS_0C03500(NCAS0C03500) NCAS_0I02120(NCAS0I02120)
NDI: NDAI_0A06780(NDAI0A06780) NDAI_0G02840(NDAI0G02840)
TPF: TPHA_0M00360(TPHA0M00360)
TBL: TBLA_0G03170(TBLA0G03170)
TDL: TDEL_0D04680(TDEL0D04680)
KAF: KAFR_0C01090(KAFR0C01090) KAFR_0F02160(KAFR0F02160)
KNG: KNAG_0K01080(KNAG0K01080) KNAG_0K01770(KNAG0K01770)
PIC: PICST_33477(RIB2)
LEL: PVL30_004594(RIB2)
CAL: CAALFM_C501940WA(CaO19.3177)
SLB: AWJ20_700(RIB2)
SOM: SOMG_04236(rib2)
CPV: cgd2_2420
 » show all
Reference
PMID:4555411
  Authors
Oltmanns O, Bacher A
  Title
Biosynthesis of riboflavine in Saccharomyces cerevisiae: the role of genes rib 1 and rib 7 .
  Journal
J Bacteriol 110:818-22 (1972)
DOI:10.1128/JB.110.3.818-822.1972
  Sequence
[sce:YOL066C]
Reference
  Authors
Behm-Ansmant I, Grosjean H, Massenet S, Motorin Y, Branlant C
  Title
Pseudouridylation at position 32 of mitochondrial and cytoplasmic tRNAs requires two distinct enzymes in Saccharomyces cerevisiae.
  Journal
J Biol Chem 279:52998-3006 (2004)
DOI:10.1074/jbc.M409581200
  Sequence
[sce:YOL066C]
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