Horsman GP, Chen Y, Thorson JS, Shen B

Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes.

Proc Natl Acad Sci U S A 107:11331-5 (2010)
DOI:10.1073/pnas.1003442107

Horsman GP, Van Lanen SG, Shen B

Iterative type I polyketide synthases for enediyne core biosynthesis.

Methods Enzymol 459:97-112 (2009)
DOI:10.1016/S0076-6879(09)04605-9

Liu W, Christenson SD, Standage S, Shen B

Biosynthesis of the enediyne antitumor antibiotic C-1027.

Science 297:1170-3 (2002)
DOI:10.1126/science.1072110

[sgb:WQO_33955]

Van Lanen SG, Oh TJ, Liu W, Wendt-Pienkowski E, Shen B

Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.

J Am Chem Soc 129:13082-94 (2007)
DOI:10.1021/ja073275o

[ag:AAQ17111]

Liu W, Nonaka K, Nie L, Zhang J, Christenson SD, Bae J, Van Lanen SG, Zazopoulos E, Farnet CM, Yang CF, Shen B

The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases.

Chem Biol 12:293-302 (2005)
DOI:10.1016/j.chembiol.2004.12.013

[ag:AAM78011]

Lohman JR, Huang SX, Horsman GP, Dilfer PE, Huang T, Chen Y, Wendt-Pienkowski E, Shen B

Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics.

Mol Biosyst 9:478-91 (2013)
DOI:10.1039/c3mb25523a

[ag:AFV52146]

Ahlert J, Shepard E, Lomovskaya N, Zazopoulos E, Staffa A, Bachmann BO, Huang K, Fonstein L, Czisny A, Whitwam RE, Farnet CM, Thorson JS

The calicheamicin gene cluster and its iterative type I enediyne PKS.

Science 297:1173-6 (2002)
DOI:10.1126/science.1072105

[ag:AAM94793]