KEGG   ORTHOLOGY: K15949
Entry
K15949            Tight     KO                                     
Symbol
aknOx
Name
aclacinomycin-N/aclacinomycin-A oxidase [EC:1.1.3.45 1.3.3.14]
Pathway
map01057  Biosynthesis of type II polyketide products
map01110  Biosynthesis of secondary metabolites
Reaction
R09334  aclacinomycin N:oxygen oxidoreductase
R09335  aclacinomycin A:oxygen oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K15949  aknOx; aclacinomycin-N/aclacinomycin-A oxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.3  With oxygen as acceptor
    1.1.3.45  aclacinomycin-N oxidase
     K15949  aknOx; aclacinomycin-N/aclacinomycin-A oxidase
  1.3  Acting on the CH-CH group of donors
   1.3.3  With oxygen as acceptor
    1.3.3.14  aclacinomycin-A oxidase
     K15949  aknOx; aclacinomycin-N/aclacinomycin-A oxidase
Genes
AG: ABI15166(aknOx)
Reference
PMID:17395717
  Authors
Alexeev I, Sultana A, Mantsala P, Niemi J, Schneider G
  Title
Aclacinomycin oxidoreductase (AknOx) from the biosynthetic pathway of the antibiotic aclacinomycin is an unusual flavoenzyme with a dual active site.
  Journal
Proc Natl Acad Sci U S A 104:6170-5 (2007)
DOI:10.1073/pnas.0700579104
  Sequence
[ag:ABI15166]
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