KEGG ORTHOLOGY: K15991

ORTHOLOGY: K15991

Entry

K15991            Tight     KO

Symbol

tylHI, CYP105L1

Name

20-oxo-5-O-mycaminosyltylactone 23-monooxygenase [EC:1.14.15.34]

Pathway

map00522

Biosynthesis of 12-, 14- and 16-membered macrolides

map01052

Type I polyketide structures

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00773

Tylosin biosynthesis, methylmalonyl-CoA + malonyl-CoA => tylactone => tylosin

Reaction

R10656

20-oxo-5-O-beta-mycaminosyltylactone,reduced ferredoxin:oxygen oxidoreductase (23-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K15991  tylHI, CYP105L1; 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K15991  tylHI, CYP105L1; 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K15991  tylHI, CYP105L1; 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase
   00199 Cytochrome P450
    K15991  tylHI, CYP105L1; 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.34  20-oxo-5-O-mycaminosyltylactone 23-monooxygenase
     K15991  tylHI, CYP105L1; 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide tailoring proteins
  Oxygenase
   K15991  tylHI, CYP105L1; 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase
Cytochrome P450 [BR:ko00199]
Cytochrome P450, bacteria type
  CYP105 family
   K15991  tylHI, CYP105L1; 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase

Other DBs

COG:

COG2124

Genes

STRE:

GZL_03700

STRM:

M444_29910