KEGG   ORTHOLOGY: K16269
Entry
K16269            Tight     KO                                     
Symbol
todD, tcbB
Name
cis-1,2-dihydrobenzene-1,2-diol/chlorobenzene dihydrodiol dehydrogenase [EC:1.3.1.19 1.3.1.119]
Pathway
map00361  Chlorocyclohexane and chlorobenzene degradation
map00362  Benzoate degradation
map00623  Toluene degradation
map00624  Polycyclic aromatic hydrocarbon degradation
map00643  Styrene degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00547  Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol
Reaction
R00812  cis-1,2-dihydrobenzene-1,2-diol:NAD+ oxidoreductase
R04088  toluene-cis-1,2-dihydrodiol:NAD+ oxidoreductase
R05354  styrene cis-glycol:NAD+ oxidoreductase
R05397  3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene:NAD+ oxidoreductase
R06832  3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene:NAD+ oxidoreductase
R06857  (1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase
R07703  1,2-dihydrophthalic acid:NAD+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol/chlorobenzene dihydrodiol dehydrogenase
   00361 Chlorocyclohexane and chlorobenzene degradation
    K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol/chlorobenzene dihydrodiol dehydrogenase
   00623 Toluene degradation
    K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol/chlorobenzene dihydrodiol dehydrogenase
   00643 Styrene degradation
    K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol/chlorobenzene dihydrodiol dehydrogenase
   00624 Polycyclic aromatic hydrocarbon degradation
    K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol/chlorobenzene dihydrodiol dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.19  cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
     K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol/chlorobenzene dihydrodiol dehydrogenase
    1.3.1.119  chlorobenzene dihydrodiol dehydrogenase
     K16269  todD, tcbB; cis-1,2-dihydrobenzene-1,2-diol/chlorobenzene dihydrodiol dehydrogenase
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K16269
Other DBs
COG: COG1028
GO: 0018504 0018501
Genes
PPF: Pput_2877
PPX: T1E_4270(tobD)
PMON: X969_10950
PMOT: X970_10605
PASI: LG197_17470(bphB)
BPT: Bpet3742(hcaB)
ATEM: PQV96_18690(bphB)
AG: AAC43636(tcbB)
Reference
PMID:2670929
  Authors
Zylstra GJ, Gibson DT
  Title
Toluene degradation by Pseudomonas putida F1. Nucleotide sequence of the todC1C2BADE genes and their expression in Escherichia coli.
  Journal
J Biol Chem 264:14940-6 (1989)
  Sequence
[ppf:Pput_2877]
Reference
PMID:8626733
  Authors
Werlen C, Kohler HP, van der Meer JR
  Title
The broad substrate chlorobenzene dioxygenase and cis-chlorobenzene dihydrodiol dehydrogenase of Pseudomonas sp. strain P51 are linked evolutionarily to the enzymes for benzene and toluene degradation.
  Journal
J Biol Chem 271:4009-16 (1996)
DOI:10.1074/jbc.271.8.4009
  Sequence
[ag:AAC43636]
LinkDB

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