KEGG ORTHOLOGY: K16339

ORTHOLOGY: K16339

Entry

K16339                      KO

Symbol

THEM4, CTMP

Name

acyl-coenzyme A thioesterase THEM4 [EC:3.1.2.2]

Pathway

map00062

Fatty acid elongation

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map04151

PI3K-Akt signaling pathway

Reaction

R09450

long-chain fatty-acyl-CoA hydrolase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K16339  THEM4, CTMP; acyl-coenzyme A thioesterase THEM4
09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K16339  THEM4, CTMP; acyl-coenzyme A thioesterase THEM4
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.2  palmitoyl-CoA hydrolase
     K16339  THEM4, CTMP; acyl-coenzyme A thioesterase THEM4

Other DBs

GO:

0016290

Genes

HSA:	117145(THEM4)

PTR:	457305(THEM4)

PPS:	100969253 100981869(THEM4)

GGO:	101140561(THEM4)

PON:	100440874(THEM4)

NLE:	100600341(THEM4)

HMH:	116469427(THEM4) 116481672

MCC:	711796(THEM4)

MCF:	102145205(THEM4)

MTHB:

126934473

MNI:	105497868(THEM4)

CSAB:

103224017

CATY:

105590243(THEM4)

PANU:

101012893(THEM4)

TGE:	112631666(THEM4)

MLEU:

105534708(THEM4)

RRO:	104681026(THEM4)

RBB:	108533212(THEM4)

TFN:	117074346 117074518(THEM4)

PTEH:

111543666(THEM4)

CANG:

105508937(THEM4)

CJC:	100400243(THEM4)

SBQ:	101034294(THEM4)

CIMI:

108316400(THEM4)

CSYR:

103263778(THEM4)

MMUR:

105873055(THEM4)

LCAT:

123635133(THEM4)

PCOQ:

105821748(THEM4)

OGA:	100964729(THEM4)

MMU:	75778(Them4)

MCAL:

110291876(Them4)

MPAH:

110320649(Them4)

RNO:	361992(Them4)

MCOC:

116093361(Them4)

ANU:	117707011(Them4)

MUN:	110565679(Them4)

CGE:	100769809(Them4)

MAUA:

106022699(Them4) 121138567

PROB:

127232747(Them4)

PLEU:

114683214(Them4)

MORG:

121437929 121450787

MFOT:

126489951

AAMP:

119801433(Them4)

NGI:	103730047(Them4)

HGL:	101703857(Them4)

CPOC:

100721204(Them4)

CCAN:

109696693(Them4)

DORD:

105984736(Them4)

DSP:	122109437(Them4)

NCAR:

124959162

MMMA:

107156619(Them4)

OCU:	100339997 103348628

OPI:	101535621(THEM4)

TUP:	102482524(THEM4)

GVR:

103607425

CFA:	609163(THEM4)

CLUD:

112663941(THEM4)

VVP:	112907787(THEM4)

VLG:	121491214(THEM4)

NPO:	129501433(THEM4)

AML:	100471932(THEM4)

UMR:	103667498(THEM4)

UAH:	113246173(THEM4)

UAR:	123787693(THEM4)

ELK:

111162045

LLV:

125098334

MPUF:

101677035(THEM4)

MNP:	132001490(THEM4)

MLK:	131809060(THEM4)

NVS:	122890259 122900522(THEM4)

ORO:	101365923(THEM4)

EJU:	114197336(THEM4)

ZCA:	113927968(THEM4)

MLX:	118000360(THEM4)

NSU:	110578501(THEM4)

FCA:	101084812(THEM4)

PYU:	121021085(THEM4)

PCOO:

112865363(THEM4)

PBG:	122481187(THEM4)

PVIV:

125159504(THEM4)

LRUF:

124515260

PTG:	102968396(THEM4)

PPAD:

109257030(THEM4)

PUC:

125912075

AJU:

106979970

HHV:	120241207(THEM4)

BTA:	787270(THEM4)

BOM:	102279271(THEM4)

BIU:	109554812(THEM4)

BBUB:

102392814(THEM4)

BBIS:

105001287(THEM4)

CHX:	102190188(THEM4)

OAS:	101119606(THEM4)

BTAX:

128045409(THEM4)

ODA:	120855860(THEM4)

CCAD:

122434847(THEM4)

MBEZ:

129541793(THEM4)

CFR:	102507666(THEM4)

CBAI:

105071701(THEM4)

CDK:	105103232(THEM4)

VPC:	102536142(THEM4)

BACU:

103002195(THEM4)

BMUS:

118892590(THEM4)

LVE:	103091662(THEM4)

OOR:	101285149(THEM4)

DLE:	111169719(THEM4)

PCAD:

102987336(THEM4)

PSIU:

116739888(THEM4)

NASI:

112411659(THEM4)

ECB:	100055681(THEM4)

EPZ:	103547926(THEM4)

EAI:	106848358(THEM4)

MYB:	102245884 102249483 102254099

MYD:	102762592(THEM4)

MMYO:

118673388(THEM4)

MLF:	102417517(THEM4) 102427328

PKL:	118727290(THEM4)

EFUS:

103291375(THEM4)

MNA:	107540780(THEM4)

DRO:	112316018(THEM4)

SHON:

118996801(THEM4)

AJM:	119048123(THEM4)

PDIC:

114489007(THEM4)

PHAS:

123804296(THEM4)

MMF:	118637684(THEM4)

PPAM:

129062334(THEM4)

HAI:	109374393(THEM4)

RFQ:	117015148(THEM4) 117019794

PALE:

102897248(THEM4)

PGIG:

120616858

PVP:	105303852(THEM4)

RAY:	107500640(THEM4)

TOD:	119236868(THEM4)

SARA:

101548074(THEM4)

SETR:

125997545(THEM4)

LAV:	100671841(THEM4)

TMU:

101360029

ETF:	101651134(THEM4)

DNM:

101414191

OAA:

100081588

GGA:	100858223(THEM4)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

ACYG:

CATA:

118260476(THEM4)

AFUL:

OTC:

PRUF:

GFR:

OMA:

PHI:	102106344(THEM4)

CCAE:

111943895

SVG:	106863862(THEM4)

CLV:	102096765(THEM4)

ACHC:

115345946

HLE:	104831371(THEM4)

AGEN:

126041123

DPUB:

104296796(THEM4)

AAM:	106492217(THEM4)

AROW:

112974558

DNE:	112981972(THEM4)

SCAM:

104139779

ASN:	102388313 102388555

AMJ:	102559435(THEM4) 109281033

CPOO:

109324823(THEM4)

PSS:	102461711(THEM4)

CMY:

CCAY:

DCC:

CPIC:

TST:

CABI:

MRV:

ACS:	100564032(them4)

ASAO:

132764213

PVT:	110081520 110081550

SUND:

121916218

PBI:	103051027(THEM4) 103053373

PMUR:

107285192 107285193 107285194

CTIG:

120316966 120316967

TSR:	106543935 106543944

PGUT:

117676287 117676290

APRI:

131186505 131186795

PTEX:

113453850 113454308 113454310

NSS:	113429117 113429118

VKO:	123032941 123032942

PMUA:

114586840(THEM4)

PRAF:

128403769

ZVI:

118076540

HCG:

128337529

GJA:	107126254 107126255 107126260 107126262

STOW:

125436620 125439233

EMC:	129325708 129325715 129330642

XLA:	443715(them4.L)

XTR:

101735170

NPR:	108797700(THEM4)

RTEM:

120920402 120920404 120920405 120920406 120920407

BBUF:

120982040 120982263

BGAR:

122921918

MUO:	115458026 115461681

GSH:	117350581(THEM4)

DRE:	791152(them4)

SRX:

SANH:

SGH:

CCAR:

CAUA:

113059639 113069342 113116219

CGIB:

127975085 128030155

PTET:

122357986 122361099(them4)

LROH:

127179061(them4)

OMC:	131522359(them4)

PPRM:

120495045(them4)

RKG:	130070499(them4)

MAMB:

125243411(them4)

CIDE:

127497475

MASI:

127453393

TROS:

130557419(them4)

TDW:	130433367(them4)

MANU:

129448171(them4)

IFU:	128610937(them4)

PHYP:

113533692

SMEO:

124385248(them4)

TFD:	113644170(them4)

TVC:	132845850(them4)

AMEX:

103035109

CMAO:

118817925(them4)

EEE:

113575243

CHAR:

105901670(them4)

TRU:

101064761

TFS:	130532576(them4)

TNG:	GSTEN00033986G001

LCO:

104923063

NCC:

104959154

TBEN:

117480579(them4)

CGOB:

115021369

PGEO:

117461085(them4)

GACU:

117554035(them4)

EMAC:

134861036(them4)

ELY:	117266078(them4)

EFO:	125892680(them4)

PLEP:

121945200(them4)

SLUC:

116049522(them4)

ECRA:

117946378(them4)

ESP:

116691712

PFLV:

114557733

GAT:	120810648(them4)

PPUG:

119197839(them4)

AFB:	129109797(them4)

CLUM:

117745336(them4)

PSWI:

130212898(them4)

MSAM:

119897620(them4)

SCHU:

122882205(them4)

CUD:	121513201(them4)

ALAT:

119005335(them4)

MZE:

101466288

ONL:

100702377

OAU:	116315660(them4)

OLA:

101172604

OML:	112143157(them4)

CSAI:

133441012(them4)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122831227(them4)

PPRL:

129371267(them4)

CVG:

107096308

CTUL:

119786686(them4)

GMU:	124864046(them4)

NFU:

107379750

KMR:	108241061(them4)

ALIM:

106533283

NWH:	119410049(them4)

AOCE:

111582981

MCEP:

125016854(them4)

POV:	109633040(them4)

SSEN:

122774205(them4)

HHIP:

117776660(them4)

HSP:	118114312(them4)

PPLT:

128450094(them4)

SMAU:

118292469(them4)

LCF:	108889573(them4)

SDU:

111237209

SLAL:

111650907

XGL:	120783706(them4)

HCQ:

109529029

SSCV:

125975429

SBIA:

133500877(them4)

PEE:	133402036(them4)

PTAO:

133479716(them4)

BPEC:

110163137

MALB:

109964143

BSPL:

114843489(them4)

SJO:	128366344(them4)

SASA:

106575342 106592246

STRU:

115176417 115186949

OTW:

121841044

OMY:	110508333(them4)

OGO:

124017014

ONE:	115118970 115121675

OKI:

109901399

OKE:

118383136

SALP:

111964813

SNH:	120048794(them4)

CCLU:

121542412(them4)

ELS:

105029233

SFM:

108924938

PKI:

111838445

AANG:

118219718(them4)

LOC:

102691049

PSPA:

121309833(them4)

ARUT:

117395476 117969132

PSEX:

120537609(them4)

PMRN:

116943050

BFO:	118408394 118412648

BBEL:

109486495

SPU:

753049

LPIC:

129276151

APLC:

110986239 110990476 110990477 110990478 110990479 110990480

SKO:

EPA:

ATEN:

AMIL:

PDAM:

SPIS:

DGT:	114529409 114529410

HMG:	100214723 100214744 101238603 105843122

TAD:	TRIADDRAFT_52537

MPP:	MICPUCDRAFT_58619(JGI:MicpuC2_58619)

GSL:	Gasu_32340 Gasu_46590

MGR:

MGG_10034

PNO:	SNOG_08299

PTE:

PTT_15054

BOR:	COCMIDRAFT_90983

ACAN:

ACA1_235040

TET:	TTHERM_00310740

PTM:	GSPATT00003881001 GSPATT00015164001 GSPATT00020511001

NGD:	NGA_0706200

SPAR:

SPRG_04086

NGR:	NAEGRDRAFT_79845

» show all

Reference

PMID:11598301

Authors

Maira SM, Galetic I, Brazil DP, Kaech S, Ingley E, Thelen M, Hemmings BA

Title

Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane.

Journal

Science 294:374-80 (2001)
DOI:10.1126/science.1062030

Sequence

[hsa:117145]

LinkDB

DBGET integrated database retrieval system