KEGG   ORTHOLOGY: K17863
Entry
K17863                      KO                                     
Symbol
PPOA
Name
linoleate 8R-lipoxygenase / 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase [EC:1.13.11.60 5.4.4.5]
Pathway
map00591  Linoleic acid metabolism
Reaction
R07061  linoleate:oxygen (8R)-oxidoreductase
R09905  (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate hydroxymutase [(5S,8R,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate-forming]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00591 Linoleic acid metabolism
    K17863  PPOA; linoleate 8R-lipoxygenase / 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.60  linoleate 8R-lipoxygenase
     K17863  PPOA; linoleate 8R-lipoxygenase / 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.4  Transferring hydroxy groups
    5.4.4.5  9,12-octadecadienoate 8-hydroperoxide 8R-isomerase
     K17863  PPOA; linoleate 8R-lipoxygenase / 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase
Other DBs
GO: 0052878
Genes
PBEL: QC761_104690
PPSD: QC762_104690
PPSP: QC763_104690
PPSA: QC764_104690
PPEI: PpBr36_02801
PGRI: PgNI_01911
CHIG: CH63R_03596
ANI: ANIA_01967
AFM: AFUA_4G10770
ACT: ACLA_049940
ABE: ARB_02272
TVE: TRV_04981
 » show all
Reference
  Authors
Brodhun F, Gobel C, Hornung E, Feussner I
  Title
Identification of PpoA from Aspergillus nidulans as a fusion protein of a fatty acid heme dioxygenase/peroxidase and a cytochrome P450.
  Journal
J Biol Chem 284:11792-805 (2009)
DOI:10.1074/jbc.M809152200
  Sequence
Reference
  Authors
Hoffmann I, Jerneren F, Garscha U, Oliw EH
  Title
Expression of 5,8-LDS of Aspergillus fumigatus and its dioxygenase domain. A comparison with 7,8-LDS, 10-dioxygenase, and cyclooxygenase.
  Journal
Arch Biochem Biophys 506:216-22 (2011)
DOI:10.1016/j.abb.2010.11.022
  Sequence
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