KEGG ORTHOLOGY: K18152

ORTHOLOGY: K18152

Entry

K18152                      KO

Symbol

BST1, CD157

Name

ADP-ribosyl cyclase 2 [GO:0050135 0003953 0061809] [EC:3.2.2.6 2.4.99.20]

Pathway

map00760

Nicotinate and nicotinamide metabolism

map01100

Metabolic pathways

map04970

Salivary secretion

map04972

Pancreatic secretion

Reaction

R00102

NAD+ glycohydrolase

R00119

NADP+:nicotinate ADP-ribosyltransferase

R10629

NAD+ nicotinamide-lyase (cyclic-ADP-ribose-forming)

R10630

cyclic-ADP-ribose hydrolase

R10631

NADP+ nicotinamide-lyase (2'-phospho-cyclic-ADP-ribose-forming)

R10632

NAADP nicotinate-lyase (2'-phospho-cyclic-ADP-ribose-forming)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K18152  BST1, CD157; ADP-ribosyl cyclase 2
09150 Organismal Systems
  09154 Digestive system
   04970 Salivary secretion
    K18152  BST1, CD157; ADP-ribosyl cyclase 2
   04972 Pancreatic secretion
    K18152  BST1, CD157; ADP-ribosyl cyclase 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K18152  BST1, CD157; ADP-ribosyl cyclase 2
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
    K18152  BST1, CD157; ADP-ribosyl cyclase 2
Enzymes [BR:ko01000]
2. Transferases
  2.4  Glycosyltransferases
   2.4.99  Transferring other glycosyl groups
    2.4.99.20  2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
     K18152  BST1, CD157; ADP-ribosyl cyclase 2
3. Hydrolases
  3.2  Glycosylases
   3.2.2  Hydrolysing N-glycosyl compounds
    3.2.2.6  ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
     K18152  BST1, CD157; ADP-ribosyl cyclase 2
CD molecules [BR:ko04090]
Proteins
  K18152  CD157, BST1; bone marrow stromal cell antigen 1
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
Enzymes
  K18152  BST1, CD157; ADP-ribosyl cyclase 2

Other DBs

GO:

0050135

Genes

HSA:

683(BST1)

PTR:	461126(BST1)

PPS:	100972434(BST1)

GGO:	101145401(BST1)

PON:	100174150(BST1)

NLE:	100606064(BST1)

HMH:	116456971(BST1)

MCC:	722848(BST1)

MCF:	101926698(BST1)

MTHB:

126955270

MNI:	105487910(BST1)

CSAB:

103246328(BST1)

CATY:

105579041(BST1)

PANU:

101017008(BST1)

TGE:	112625503(BST1)

MLEU:

105542551(BST1)

RRO:	104658167(BST1)

RBB:	108531746(BST1)

TFN:	117085172(BST1)

PTEH:

111539163(BST1)

CANG:

105516575(BST1)

CJC:	100402445(BST1)

SBQ:	101035567(BST1)

CIMI:

108282733(BST1)

CSYR:

103269336(BST1)

MMUR:

105856080(BST1)

LCAT:

123637314(BST1)

PCOQ:

105805514(BST1)

OGA:	100949639(BST1)

MMU:	12182(Bst1)

MCAL:

110294333(Bst1)

MPAH:

110330979(Bst1)

RNO:	81506(Bst1)

MCOC:

116070677(Bst1)

ANU:	117712864(Bst1)

MUN:	110559149(Bst1)

CGE:	100773468(Bst1)

MAUA:

101829693(Bst1)

PROB:

127233691(Bst1)

PLEU:

114709224(Bst1)

MORG:

121436585(Bst1)

MFOT:

126506474

AAMP:

119803349(Bst1)

NGI:	103728884(Bst1)

HGL:	101713685(Bst1)

CPOC:

100726264(Bst1) 100735470

CCAN:

109691564(Bst1)

DORD:

105980149(Bst1)

DSP:	122104071(Bst1)

PLOP:

125364481(Bst1)

NCAR:

124994678

MMMA:

107139141(Bst1)

OCU:

100351817

OPI:	101533472(BST1)

TUP:	102468679(BST1)

GVR:	103606370(BST1)

CLUD:

125752080(BST1)

VVP:	112919977(BST1)

VLG:	121489283(BST1)

NPO:	129510478(BST1)

AML:	100463977(BST1)

UMR:	103658313(BST1)

UAH:	113266702(BST1)

UAR:	123775810(BST1)

ELK:

111149117

LLV:

125093560

MPUF:

101684892(BST1)

MNP:	132004743(BST1)

MLK:	131825787(BST1)

NVS:	122890462(BST1)

ORO:	101365133(BST1)

EJU:	114198536(BST1)

ZCA:	113924929(BST1)

MLX:	118010690(BST1)

NSU:	110581065(BST1)

LWW:	102748987(BST1)

FCA:	101101052(BST1)

PYU:	121038087(BST1)

PCOO:

112858650(BST1)

PBG:	122479021(BST1)

PVIV:

125164330(BST1)

LRUF:

124521280

PTG:	102962771(BST1)

PPAD:

109269636(BST1)

PUC:

125922651

AJU:

106975627

HHV:	120237994(BST1)

BTA:	616757(BST1)

BOM:	102271683(BST1)

BIU:	109560088(BST1)

BBUB:

102400853(BST1)

BBIS:

105001197(BST1)

CHX:	102169848(BST1)

OAS:	101116575(BST1)

BTAX:

128049684(BST1)

ODA:	120861770(BST1)

CCAD:

122428330(BST1)

SSC:	100625942(BST1)

CFR:	102508256(BST1)

CBAI:

105083238(BST1)

CDK:	105098338(BST1)

VPC:	102538089(BST1)

BACU:

103000954(BST1)

BMUS:

118895232(BST1)

LVE:	103088314(BST1)

OOR:	101284786(BST1)

DLE:	111171425(BST1)

PCAD:

102982819(BST1)

PSIU:

116754525(BST1)

NASI:

112397568(BST1)

ECB:	100068968(BST1)

EPZ:	103565758(BST1)

EAI:	106827092(BST1)

MYB:	102252530(BST1)

MYD:	102770056(BST1)

MMYO:

118666927(BST1)

MLF:	102437542(BST1)

PKL:	118725690(BST1)

EFUS:

103294530(BST1)

DRO:	112316691(BST1)

SHON:

118989556(BST1)

AJM:	119035581(BST1)

PDIC:

114493375(BST1)

PHAS:

123815824(BST1)

MMF:	118615378(BST1)

PPAM:

129077456(BST1)

HAI:	109372831(BST1)

RFQ:	117022444(BST1)

PALE:

102884937(BST1)

PGIG:

120582708(BST1)

PVP:	105295961(BST1)

RAY:	107507352(BST1)

MJV:	108403411(BST1)

TOD:	119260888(BST1)

SARA:

101539895(BST1)

SETR:

126032568(BST1)

LAV:	100659997(BST1)

TMU:

101346112

ETF:	101649299 101649935

DNM:	101429299(BST1)

MDO:	100015733(BST1)

GAS:	123252450(BST1)

SHR:	100915627(BST1)

AFZ:

127540591

PCW:	110212831(BST1)

OAA:	100079912(BST1)

GGA:	422828(BST1)

PCOC:

116225809(BST1)

MGP:

100546297

CJO:	107313950(BST1)

TPAI:

128080300(BST1)

LMUT:

125691785

NMEL:

110398576

ACYG:

106035386(BST1)

CATA:

118259455

AFUL:

116489206

TGU:	100224783(BST1)

LSR:

110484039

SCAN:

103824309(BST1)

PMOA:

120497359

OTC:

121335188

PRUF:

121348778(BST1)

GFR:	102032481(BST1)

FAB:	101808664(BST1)

OMA:	130252873(BST1)

PHI:

PMAJ:

CCAE:

CCW:

CBRC:

ETL:	114061133(BST1)

ZAB:

102061886

ACHL:

103810025(BST1)

SVG:	106857245(BST1)

MMEA:

130578391

HRT:

120753271

FPG:	101917967(BST1)

FCH:

102048871

CLV:	102089855(BST1)

EGZ:	104134476(BST1)

NNI:	104010764(BST1)

PCRI:

104030339(BST1)

PLET:

104619105(BST1)

EHS:	104508986(BST1)

PCAO:

104040776(BST1)

ACUN:

113479383(BST1)

TALA:

104360998(BST1)

PADL:

103916997(BST1)

AFOR:

103898760

ACHC:

115341987(BST1)

HALD:

104312688(BST1)

HLE:	104837599(BST1)

AGEN:

126034359

GCL:

127015977

CCRI:

104163056(BST1)

CMAC:

104475413(BST1)

MUI:	104536118(BST1)

BREG:

104631650(BST1)

GSTE:

104263570(BST1)

LDI:	104353367(BST1)

MNB:	103776747(BST1)

OHA:	104329232(BST1)

SHAB:

115610662(BST1)

DPUB:

104309172(BST1)

PGUU:

104461953(BST1)

ACAR:

104523533

CPEA:

104393587(BST1)

AVIT:

104272885(BST1)

CVF:	104288764(BST1)

RTD:

128910295

CUCA:

104067702(BST1)

TEO:	104376417(BST1)

BRHI:

104500705(BST1)

AAM:

106498751

AROW:

112970832

NPD:

112958511

TGT:	104569372(BST1)

DNE:

112996530

SCAM:

104143028(BST1)

ASN:	102376962(BST1)

AMJ:	102559494(BST1)

CPOO:

109322214(BST1)

GGN:

109303956

PSS:	102444728(BST1)

CMY:	102933631(BST1)

CCAY:

125636146(BST1)

DCC:	119855170(BST1)

CPIC:

101935271

TST:

117878553

CABI:

116821061(BST1)

MRV:

120405962

XLA:	101027297(bst1.L)

XTR:

101733556

NPR:	108799310(BST1)

RTEM:

120924335

BBUF:

120990332

BGAR:

122940253(BST1)

MUO:	115461420(BST1)

AANG:

PSPA:

ARUT:

RTP:

CPLA:

HOC:

LERI:

PMRN:

LRJ:	133345413 133345610

BBEL:

109465410

APLC:

110977913

SKO:

100370260

LGI:	LOTGIDRAFT_150043

PVUL:

126821660 126830888

PCAN:

112555169 112555726

GAE:

121367392

HRF:	124117015 124117017 124122531

HRJ:	124262801 124267312

CRG:

CVN:

CANU:

OED:

PMAX:

MMER:

RPHI:

DPOL:

LAK:	106153853 106155009 106155798 106159481 106159482 106169313 106180219

NVE:	116618638 5503859

ATEN:

ADF:

AMIL:

XEN:

HSY:

TAD:	TRIADDRAFT_19184

AQU:	105312071 105312710

» show all

Reference

PMID:8202488

Authors

Kaisho T, Ishikawa J, Oritani K, Inazawa J, Tomizawa H, Muraoka O, Ochi T, Hirano T

Title

BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth.

Journal

Proc Natl Acad Sci U S A 91:5325-9 (1994)
DOI:10.1073/pnas.91.12.5325

Sequence

[hsa:683]

Reference

PMID:23576305

Authors

Quarona V, Zaccarello G, Chillemi A, Brunetti E, Singh VK, Ferrero E, Funaro A, Horenstein AL, Malavasi F

Title

CD38 and CD157: a long journey from activation markers to multifunctional molecules.

Journal

Cytometry B Clin Cytom 84:207-17 (2013)
DOI:10.1002/cyto.b.21092

Reference

PMID:12415565

Authors

Ortolan E, Vacca P, Capobianco A, Armando E, Crivellin F, Horenstein A, Malavasi F

Title

CD157, the Janus of CD38 but with a unique personality.

Journal

Cell Biochem Funct 20:309-22 (2002)
DOI:10.1002/cbf.978

Sequence

[hsa:683]

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