KEGG   ORTHOLOGY: K18389
Entry
K18389                      KO                                     
Symbol
PAXQ, ATMQ, CYP698A
Name
cytochrome P450 monooxygenase [EC:1.14.13.-]
Pathway
map00403  Indole diterpene alkaloid biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R10359  13-desoxypaxilline,NADPH:oxygen oxidoreductase
R10361  
R10362  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00403 Indole diterpene alkaloid biosynthesis
    K18389  PAXQ, ATMQ, CYP698A; cytochrome P450 monooxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K18389  PAXQ, ATMQ, CYP698A; cytochrome P450 monooxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, fungi type
  CYP698 family
   K18389  PAXQ, ATMQ, CYP698A; cytochrome P450 monooxygenase
Other DBs
COG: COG2124
Genes
AOR: AO090011000739
AFV: AFLA_008139
POU: POX_c04253
AG: AAK11527(PAXQ)
Reference
  Authors
Tagami K, Minami A, Fujii R, Liu C, Tanaka M, Gomi K, Dairi T, Oikawa H
  Title
Rapid reconstitution of biosynthetic machinery for fungal metabolites in Aspergillus oryzae: total biosynthesis of aflatrem.
  Journal
Chembiochem 15:2076-80 (2014)
DOI:10.1002/cbic.201402195
Reference
  Authors
Nicholson MJ, Koulman A, Monahan BJ, Pritchard BL, Payne GA, Scott B
  Title
Identification of two aflatrem biosynthesis gene loci in Aspergillus flavus and metabolic engineering of Penicillium paxilli to elucidate their function.
  Journal
Appl Environ Microbiol 75:7469-81 (2009)
DOI:10.1128/AEM.02146-08
  Sequence
Reference
  Authors
Young C, McMillan L, Telfer E, Scott B
  Title
Molecular cloning and genetic analysis of an indole-diterpene gene cluster from Penicillium paxilli.
  Journal
Mol Microbiol 39:754-64 (2001)
DOI:10.1046/j.1365-2958.2001.02265.x
  Sequence
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