KEGG   ORTHOLOGY: K18686
Entry
K18686                      KO                                     
Symbol
cotB2
Name
cyclooctat-9-en-7-ol synthase [EC:4.2.3.146]
Pathway
map00997  Biosynthesis of various other secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00921  Cyclooctatin biosynthesis, dimethylallyl-PP + isopentenyl-PP => cyclooctatin
Reaction
R10763  geranylgeranyl-diphosphate diphosphate-lyase (cyclooctat-9-en-7-ol-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00997 Biosynthesis of various other secondary metabolites
    K18686  cotB2; cyclooctat-9-en-7-ol synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.3  Acting on phosphates
    4.2.3.146  cyclooctat-9-en-7-ol synthase
     K18686  cotB2; cyclooctat-9-en-7-ol synthase
Genes
SVL: Strvi_5779
SRC: M271_43275
SMAL: SMALA_0742
SSOI: I1A49_07300
SCI: B446_28660
SRN: A4G23_04517
SAUO: BV401_07560
SFB: CP974_24295
SANT: QR300_36895
SOV: QZH56_30185
AG: BAI44338(cotB2)
 » show all
Reference
  Authors
Kim SY, Zhao P, Igarashi M, Sawa R, Tomita T, Nishiyama M, Kuzuyama T
  Title
Cloning and heterologous expression of the cyclooctatin biosynthetic gene cluster afford a diterpene cyclase and two p450 hydroxylases.
  Journal
Chem Biol 16:736-43 (2009)
DOI:10.1016/j.chembiol.2009.06.007
  Sequence
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