KEGG   ORTHOLOGY: K18767
Entry
K18767            Tight     KO                                     
Symbol
blaCTX-M
Name
beta-lactamase class A CTX-M [EC:3.5.2.6]
Pathway
map01501  beta-Lactam resistance
Reaction
R06363  penicillin hydrolase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K18767  blaCTX-M; beta-lactamase class A CTX-M
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K18767  blaCTX-M; beta-lactamase class A CTX-M
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.6  beta-lactamase
     K18767  blaCTX-M; beta-lactamase class A CTX-M
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  beta-Lactamase genes
   Class A [MT]
    K18767  blaCTX-M; beta-lactamase class A CTX-M
Antimicrobial resistance: KEGG signatures [br01600.html]
 Signature KOs for antimicrobial resistance
  K18767
Other DBs
COG: COG2367
GO: 0008800
Genes
ESL: O3K_25787
ECOS: EC958_A0119(blaCTX-M-15)
ECOJ: P423_07345
ERUY: OSH18_21085
KPM: KPHS_p100340 KPHS_p301310
KPY: KPNIH31_23215
KPJ: N559_5233
KPX: PMK1_04637(bla_2) PMK1_ndm00052(bla_1)
KPB: FH42_25820
KOE: A225_R1p0210
KLW: DA718_21395
CIE: AN232_26695(blaCTX-M)
KAS: KATP_12750(kluA)
KLU: K7B04_22580(blaCTX-M)
KCY: RIN60_06905
METY: MRY16398_p20490(blaCTX-M-2)
PRQ: CYG50_00765
MWI: MNY66_17545
VCQ: EN18_05780
AVZ: HWI77_19305
SBJ: CF168_21180
VG: 29081721(BI168_gp066)
AG: AAC32890(CTX-M-5) AAF04388(CTX-M-8) AAF05311(CTX-M-9) AAF65843(CTX-M-10) AAF72530(CTX-M-14) AAF72531(CTX-M-13) AAG34108(CTX-M-12) AAK32961(CTX-M-16) AAK55533(CTX-M-18) AAK55534(CTX-M-19) AAK71471(CTX-M-17) AAL02127(CTX-M-15) AAL86924(CTX-M-22) AAL99990(CTX-M-23) AAM70498(CTX-M-25) AAN75444(CTX-M-26) AAO61597(CTX-M-27) AAO88912(CTX-M-33) AAP22736(CTX-M-29) AAP43508(CTX-M-30) AAR99493(CTX-M-34) AAV28215(CTX-M-40) AAV97952(CTX-M-47) AAV97953(CTX-M-48) AAV97954(CTX-M-49) AAV97955(CTX-M-50) AAV97956(CTX-M-46) AAV97957(CTX-M-72) AAX33264(CTX-M-37) AAX54694(CTX-M-39) AAY43008(CTX-M-41) AAY84742(CTX-M-42) AAZ14955(CTX-M-43) ABB59946(CTX-M-82) ABB72225(CTX-M-53) ABC18328(CTX-M-54) ABD73290(CTX-M-59) ABG80523(CTX-M-57) ABI34705(CTX-M-55) ABN09669(CTX-M-61) ABN48311(CTX-M-56) ABO09821(CTX-M-79) ABP04245(CTX-M-62) ABQ45409(CTX-M-66) ABS90365(CTX-M-67) ABV57756(CTX-M-81) ABV81082(CTX-M-68) ABW86620(CTX-M-80) ABW87621(CTX-M-65) ABY91281(CTX-M-69) ACB41777(CTX-M-87) ACI29345(CTX-M-83) ACI29346(CTX-M-84) ACI29347(CTX-M-85) ACI29348(CTX-M-86) ACP18863(CTX-M-88) ACR56321(CTX-M-89) ACS32293(CTX-M-74) ACS32294(CTX-M-75) ACV92002(CTX-M-71) ACY74743(CTX-M-92) ADK11041(CTX-M-94) ADM08178(CTX-M-97) ADN26580(CTX-M-93) ADO17948(CTX-M-98) ADY02545(CTX-M-101) ADY02546(CTX-M-102) ADY02554(CTX-M-105) ADY02555(CTX-M-104) ADZ31262(CTX-M-106) AEI70324(CTX-M-116) AEM44648(CTX-M-110) AEM44649(CTX-M-111) AEM44650(CTX-M-107) AEM44651(CTX-M-108) AEM44652(CTX-M-112) AEM44653(CTX-M-113) AEM44654(CTX-M-109) AET99223(CTX-M-117) AEW46676(CTX-M-131) AFA51699(CTX-M-121) AFA51701(CTX-M-123) AFH88134(CTX-M-124) AFQ94051(CTX-M-132) AHA80107(CTX-M-138) AHC31002(CTX-M-137) AHX39588(CTX-M-144) AHX39589(CTX-M-148) AIT97310(CTX-M-158) AOF41435(CTX-M-190) ARQ19295(CTX-M-199) BAA07082(CTX-M-44) BAA28282(CTX-M-45) BAF63422(CTX-M-64) BAL72196(CTX-M-126) CAA06311(CTX-M-6) CAA06312(CTX-M-7) CAA63262(CTX-M-1) CAA63263(CTX-M-2) CAA71321(CTX-M-3) CAA74573(CTX-M-4) CAC95175(CTX-M-20) CAD08929(CTX-M-21) CAD70280(CTX-M-28) CAD89606(CTX-M-32) CAD99181(CTX-M-31) CAJ00132(CTX-M-24) CAQ42481(CTX-M-78) CBW46935(CTX-M-100) CDG50843(CTX-M-103)
 » show all
Reference
PMID:8834913
  Authors
Bauernfeind A, Stemplinger I, Jungwirth R, Ernst S, Casellas JM
  Title
Sequences of beta-lactamase genes encoding CTX-M-1 (MEN-1) and CTX-M-2 and relationship of their amino acid sequences with those of other beta-lactamases.
  Journal
Antimicrob Agents Chemother 40:509-13 (1996)
DOI:10.1128/AAC.40.2.509
  Sequence
[ag:CAA63262]
Reference
PMID:11585791
  Authors
Bradford PA
  Title
Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat.
  Journal
Clin Microbiol Rev 14:933-51, table of contents (2001)
DOI:10.1128/CMR.14.4.933-951.2001
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