KEGG   ORTHOLOGY: K18780
Entry
K18780            Tight     KO                                     
Symbol
blaNDM
Name
metallo-beta-lactamase class B NDM [EC:3.5.2.6]
Pathway
map01501  beta-Lactam resistance
Module
M00851  Carbapenem resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K18780  blaNDM; metallo-beta-lactamase class B NDM
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K18780  blaNDM; metallo-beta-lactamase class B NDM
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.6  beta-lactamase
     K18780  blaNDM; metallo-beta-lactamase class B NDM
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  beta-Lactamase genes
   Class B [MT]
    K18780  blaNDM; metallo-beta-lactamase class B NDM
Antimicrobial resistance: KEGG signatures [br01600.html]
 Signature KOs for antimicrobial resistance
  K18780
Other DBs
COG: COG0491
GO: 0008800
Genes
KPX: PMK1_ndm00067(blaNDM-1_1) PMK1_ndm00076(blaNDM-1_2) PMK1_ndm00085(blaNDM-1_3)
KPB: FH42_25895
KOE: A225_NDM1p0330
CSED: JY391_23210
CIE: AN232_29410
PRG: RB151_P104578(blaNDM-1)
PVC: G3341_20200
PJU: L1P09_08610
DCE: O6P33_04925
ABAZ: AFM77866.1(blaNDM-1)
ANO: RR32_18615
ADV: DJ533_14545
AWU: BEN71_10660
ACUM: C9E88_015555
ACHI: CDG60_00315
APOT: MZO21_14000
SHEJ: MZ182_20600
AAEG: RA224_14625
AG: AEA41876(NDM-2) AEN03071(NDM-5) AEX08599(NDM-6) AFB82585(NDM-4) AFK80349(NDM-3) AGK06434(NDM-7) AGU91756(NDM-9) AJP18054(NDM-14) AOT73359(NDM-17) AQY45923(NDM-20) BAM84089(NDM-8) BAO79439(NDM-12) BAQ02518(NDM-13) CAZ39946(NDM-1)
 » show all
Reference
PMID:19770275
  Authors
Yong D, Toleman MA, Giske CG, Cho HS, Sundman K, Lee K, Walsh TR
  Title
Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India.
  Journal
Antimicrob Agents Chemother 53:5046-54 (2009)
DOI:10.1128/AAC.00774-09
  Sequence
[ag:CAZ39946]
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