KEGG   ORTHOLOGY: K18793
Entry
K18793            Tight     KO                                     
Symbol
blaOXA-23
Name
beta-lactamase class D OXA-23 [EC:3.5.2.6]
Pathway
map01501  beta-Lactam resistance
Module
M00851  Carbapenem resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K18793  blaOXA-23; beta-lactamase class D OXA-23
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K18793  blaOXA-23; beta-lactamase class D OXA-23
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.6  beta-lactamase
     K18793  blaOXA-23; beta-lactamase class D OXA-23
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  beta-Lactamase genes
   Class D [MT]
    K18793  blaOXA-23; beta-lactamase class D OXA-23
Antimicrobial resistance: KEGG signatures [br01600.html]
 Signature KOs for antimicrobial resistance
  K18793
Other DBs
COG: COG2602
GO: 0008800 0008658
Genes
ABN: AB57_06435(oxa23) AB57_06525(oxa23)
ABZ: ABZJ_01990
ABR: ABTJ_p0085
ABD: ABTW07_2597
ABJ: BJAB07104_01927
ABAB: BJAB0715_00989
ABAJ: BJAB0868_01950
ABAU: IX87_16825 IX87_21860
ABW: BL01_p0470
ARJ: DOM24_04840
AG: 18195058-1(OXA-102) 18195058-2(OXA-103) 18195058-3(OXA-105) AAG35609(OXA-27) ACE63186(OXA-133) ACI28281(OXA-146) CAB69042(OXA-23)
 » show all
Reference
PMID:10602749
  Authors
Donald HM, Scaife W, Amyes SG, Young HK
  Title
Sequence analysis of ARI-1, a novel OXA beta-lactamase, responsible for imipenem resistance in Acinetobacter baumannii 6B92.
  Journal
Antimicrob Agents Chemother 44:196-9 (2000)
DOI:10.1128/AAC.44.1.196-199.2000
  Sequence
[ag:CAB69042]
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