KEGG   ORTHOLOGY: K18824
Entry
K18824                      KO                                     
Symbol
sul2
Name
dihydropteroate synthase type 2 [EC:2.5.1.15]
Pathway
map00790  Folate biosynthesis
map01100  Metabolic pathways
Reaction
R03066  6-(hydroxymethyl)-7,8-dihydropterin:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase
R03067  (7,8-dihydropterin-6-yl)methyl diphosphate:4-aminobenzoate 2-amino-4-hydroxy-7,8-dihydropteridine-6-methenyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    K18824  sul2; dihydropteroate synthase type 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K18824  sul2; dihydropteroate synthase type 2
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.15  dihydropteroate synthase
     K18824  sul2; dihydropteroate synthase type 2
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  Sulfonamide resistance genes
   Dihydropteroate synthase
    K18824  sul2; dihydropteroate synthase type 2
Other DBs
COG: COG0294
GO: 0004156
Genes
EOI: ECO111_p1-124
ECOO: ECRM13514_5831(sulII)
ESL: O3K_00470
ESO: O3O_25220
ESM: O3M_00480
ECG: E2348_P2_01(sulII)
ELR: ECO55CA74_26384
ECW: EcE24377A_B0005(folP2)
EUN: pUMNK88_45(sul2)
ECM: EcSMS35_A0127(sul2)
ELN: NRG857_30095
ECOI: ECOPMV1_p00057(folP)
ERUY: OSH18_21045(sul2)
STY: HCM1.222
SEY: SL1344_P3_0001(sulII)
SEM: STMDT12_S00050
SEB: STM474_p301(folP)
SETU: STU288_2p00035
SETC: CFSAN001921_24005
SEE: SNSL254_p_0047(sul2)
SEW: SeSA_B0090(sul2)
SFX: S2703
SFE: SFxv_5150
SSN: SSON_PA03(sulII)
ENC: ECL_03814
ECLY: LI62_012670
ECLA: ECNIH3_23420
KPN: KPN_pKPN5p08183(sul)
KPM: KPHS_p300880
KPG: KPNIH32_27965
KPA: KPNJ1_05661
KPB: FH42_26495
KOE: A225_1930 A225_R1p0385
KOK: KONIH1_31675
EAR: CCG28638
KLW: DA718_21540(sul2)
KPAS: LUW96_29790(sul2)
CFQ: C2U38_26770
CFAR: CI104_27365(folP)
CIR: C2U53_02830
CITZ: E4Z61_00210(sul2)
CIX: M4I31_16815(sul2)
YRE: HEC60_24055(sul2)
KIN: AB182_02820
PCOL: F1325_16060(sul2)
PCIB: F9282_16435(sul2)
PSX: DR96_3355(folP)
PSTA: BGK56_20705
PTHA: OI982_22230(sul2)
PRG: RB151_016360(folP_1)
PRQ: CYG50_01290(sul2)
MWI: MNY66_17515(sul3)
ETR: ETAE_p041(folP)
ETE: ETEE_p1022(folP)
PMV: PMCN06_p03(sulII)
PMP: Pmu_02780(sul2)
MHX: MHH_c22580(sulII)
APA: APP7_B0003(folP)
AIO: EXH44_00890(sul2)
BTO: WQG_1040
BTRH: F543_22820
BTRA: F544_3040 F544_3100
THES: FHQ07_00750(sul2)
VCF: IR04_08335
VCE: Vch1786_I0086(sul2)
VCQ: EN18_05275 EN18_06335 EN18_06385
VCJ: VCD_003730
VTU: IX91_25305
VNL: D3H41_03140(sul2)
PPUH: B479_26869
DCE: O6P33_04535(sul2) O6P33_04950(sul2)
ACB: A1S_0675
ABX: ABK1_0255
ABZ: ABZJ_04360(sul2)
ABR: ABTJ_03576
ABD: ABTW07_2427
ABH: M3Q_464
ABJ: BJAB07104_00246
ABAB: BJAB0715_02885
ABAJ: BJAB0868_00253
ABAZ: P795_18065
ABK: LX00_17470
ABAU: IX87_13165
ABAA: IX88_03750
ABAL: ABLAC_01210
AJO: RZ95_19290
ADV: DJ533_00920(sul2)
AWU: BEN71_00450(sul2)
ACUM: C9E88_016590(sul2)
ATG: J4G44_12820(sul2) J4G44_12915(sul2)
AVB: RYU24_23330
APOT: MZO21_09680(sul2) MZO21_14020(sul2)
MBL: AAX09_10050 AAX09_10115
SBJ: CF168_22035(folP)
SALG: BS332_22260
SAES: HBH39_17955(sul2)
SHEJ: MZ182_20710(sul2)
RHH: E0Z06_12435(sul2)
AXE: P40_05820
APAC: S7S_03825
ASIM: FE240_08965(sul2)
SINI: GT972_03210(sul2)
NSI: A6J88_09485
KKI: KKKWG1_0923(sulII)
AXN: AX27061_3444
AXX: ERS451415_03438(folP_1)
AALN: Q3V95_09605(sul2)
AFQ: AFA_07950(folP)
OUE: I6G29_00075(sul2)
MELA: C6568_16875
NST: Nstercoris_00020
ATW: C0099_10055
PLA: Plav_2130
PMOB: HG718_02075(folP)
PECT: BN1012_Phect685
RBS: RHODOSMS8_02197(folP)
PAEZ: PAE61_06740(sul2)
GEH: HYN69_19865 HYN69_20400
NRE: BES08_30320 BES08_30755
SGI: SGRAN_1316(sulII)
CCJZ: ccrud_14620
CKW: CKALI_00270(folP1)
SRJ: SRO_6336
SGF: HEP81_06685(folP_3)
AMYC: CU254_37230(folP)
GVI: glr0540(folP)
GLJ: GKIL_3177(folP)
GML: ISF26_16465(folP)
VBC: C5Q97_04130
LBJ: LBJ_0045(folP)
LBL: LBL_2999(folP)
LST: LSS_14376
LMAY: DPV73_05230(folP)
LKM: EFP84_11120(folP)
LWL: FHG68_00245(folP)
MOD: AS202_15175
MALS: NWE55_16710(sul2)
CTAK: 4412677_02201(folP_1)
CSUP: MTP09_11370(sul2)
CHRA: F7R58_01285(sul2)
AG: AAS18380(sul2)
 » show all
Reference
PMID:23641240
  Authors
Suzuki S, Ogo M, Miller TW, Shimizu A, Takada H, Siringan MA
  Title
Who possesses drug resistance genes in the aquatic environment?: sulfamethoxazole (SMX) resistance genes among the bacterial community in water environment of Metro-Manila, Philippines.
  Journal
Front Microbiol 4:102 (2013)
DOI:10.3389/fmicb.2013.00102
Reference
PMID:25405870
  Authors
Wang N, Yang X, Jiao S, Zhang J, Ye B, Gao S
  Title
Sulfonamide-resistant bacteria and their resistance genes in soils fertilized with manures from jiangsu province, southeastern china.
  Journal
PLoS One 9:e112626 (2014)
DOI:10.1371/journal.pone.0112626
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