KEGG   ORTHOLOGY: K18825
Entry
K18825                      KO                                     
Symbol
sul3
Name
dihydropteroate synthase type 3 [EC:2.5.1.15]
Pathway
map00790  Folate biosynthesis
map01100  Metabolic pathways
Reaction
R03066  6-(hydroxymethyl)-7,8-dihydropterin:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase
R03067  (7,8-dihydropterin-6-yl)methyl diphosphate:4-aminobenzoate 2-amino-4-hydroxy-7,8-dihydropteridine-6-methenyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    K18825  sul3; dihydropteroate synthase type 3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K18825  sul3; dihydropteroate synthase type 3
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.15  dihydropteroate synthase
     K18825  sul3; dihydropteroate synthase type 3
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  Sulfonamide resistance genes
   Dihydropteroate synthase
    K18825  sul3; dihydropteroate synthase type 3
Other DBs
COG: COG0294
GO: 0004156
Genes
SETU: STU288_1p00720
SEC: SCH_048(sulII)
SEW: SeSA_B0060(folP)
KPNE: KU54_01050
AG: CAD30683(sul3)
Reference
PMID:23641240
  Authors
Suzuki S, Ogo M, Miller TW, Shimizu A, Takada H, Siringan MA
  Title
Who possesses drug resistance genes in the aquatic environment?: sulfamethoxazole (SMX) resistance genes among the bacterial community in water environment of Metro-Manila, Philippines.
  Journal
Front Microbiol 4:102 (2013)
DOI:10.3389/fmicb.2013.00102
Reference
PMID:25405870
  Authors
Wang N, Yang X, Jiao S, Zhang J, Ye B, Gao S
  Title
Sulfonamide-resistant bacteria and their resistance genes in soils fertilized with manures from jiangsu province, southeastern china.
  Journal
PLoS One 9:e112626 (2014)
DOI:10.1371/journal.pone.0112626
LinkDB

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