KEGG   ORTHOLOGY: K18970
Entry
K18970            Tight     KO                                     
Symbol
blaGES
Name
beta-lactamase class A GES [EC:3.5.2.6]
Pathway
map01501  beta-Lactam resistance
Module
M00851  Carbapenem resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K18970  blaGES; beta-lactamase class A GES
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K18970  blaGES; beta-lactamase class A GES
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.6  beta-lactamase
     K18970  blaGES; beta-lactamase class A GES
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  beta-Lactamase genes
   Class A [MT]
    K18970  blaGES; beta-lactamase class A GES
Antimicrobial resistance: KEGG signatures [br01600.html]
 Signature KOs for antimicrobial resistance
  K18970
Other DBs
COG: COG2367
GO: 0008800
Genes
AG: AAF27723(GES-1) AAF28763(GES-7) AAK18183(GES-8) AAK58421(GES-2) AAR97270(GES-5) AAR97271(GES-6) AAY43207(GES-9) ACS44714(GES-11) ACS73598(GES-10) ACZ54536(GES-13) ADC91899(GES-14) ADP21506(GES-12) AEX59144(GES-18) AEZ05107(GES-19) AEZ05108(GES-20) AFU25739(GES-22) AMY16492(GES-31) AOE46846(GES-32) BAD06399(GES-3) BAD08689(GES-4)
Reference
PMID:10681329
  Authors
Poirel L, Le Thomas I, Naas T, Karim A, Nordmann P
  Title
Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae.
  Journal
Antimicrob Agents Chemother 44:622-32 (2000)
DOI:10.1128/AAC.44.3.622-632.2000
  Sequence
[ag:AAF27723]
Reference
PMID:20525990
  Authors
Poirel L, Carattoli A, Bernabeu S, Bruderer T, Frei R, Nordmann P
  Title
A novel IncQ plasmid type harbouring a class 3 integron from Escherichia coli.
  Journal
J Antimicrob Chemother 65:1594-8 (2010)
DOI:10.1093/jac/dkq166
LinkDB

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