KEGG   ORTHOLOGY: K18972
Entry
K18972            Tight     KO                                     
Symbol
blaOXA-58
Name
beta-lactamase class D OXA-58 [EC:3.5.2.6]
Pathway
map01501  beta-Lactam resistance
Module
M00851  Carbapenem resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K18972  blaOXA-58; beta-lactamase class D OXA-58
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K18972  blaOXA-58; beta-lactamase class D OXA-58
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.6  beta-lactamase
     K18972  blaOXA-58; beta-lactamase class D OXA-58
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  beta-Lactamase genes
   Class D [MT]
    K18972  blaOXA-58; beta-lactamase class D OXA-58
Antimicrobial resistance: KEGG signatures [br01600.html]
 Signature KOs for antimicrobial resistance
  K18972
Other DBs
COG: COG2602
GO: 0008800 0008658
Genes
ABC: ACICU_p0019 ACICU_p0024
ABAB: BJAB0715_p0053
AJO: RZ95_19145
ADV: DJ533_02250
ACHI: CDG60_00590
ATG: J4G44_13030
APOT: MZO21_14820
AG: AAW57529(OXA-58) ABF47919(OXA-96) ABO33299(OXA-97) ADK34116(OXA-164)
Reference
PMID:15616297
  Authors
Poirel L, Marque S, Heritier C, Segonds C, Chabanon G, Nordmann P
  Title
OXA-58, a novel class D {beta}-lactamase involved in resistance to carbapenems in Acinetobacter baumannii.
  Journal
Antimicrob Agents Chemother 49:202-8 (2005)
DOI:10.1128/AAC.49.1.202-208.2005
  Sequence
[ag:AAW57529]
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