KEGG ORTHOLOGY: K18974

ORTHOLOGY: K18974

Entry

K18974                      KO

Symbol

sul1

Name

dihydropteroate synthase type 1 [EC:2.5.1.15]

Pathway

map00790

Folate biosynthesis

map01100

Metabolic pathways

Reaction

R03066

6-(hydroxymethyl)-7,8-dihydropterin:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase

R03067

(7,8-dihydropterin-6-yl)methyl diphosphate:4-aminobenzoate 2-amino-4-hydroxy-7,8-dihydropteridine-6-methenyltransferase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    K18974  sul1; dihydropteroate synthase type 1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K18974  sul1; dihydropteroate synthase type 1
Enzymes [BR:ko01000]
2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.15  dihydropteroate synthase
     K18974  sul1; dihydropteroate synthase type 1
Antimicrobial resistance genes [BR:ko01504]
Gene variants
  Sulfonamide resistance genes
   Dihydropteroate synthase
    K18974  sul1; dihydropteroate synthase type 1

Other DBs

COG:

COG0294

GO:

0004156

Genes

ECOO:

ESL:

ESO:

ESM:

EUN:	pUMNK88_135(sul1) pUMNK88_37

ECOS:

EC958_A0111(sulI)

ECV:	APECO1_O1R95(sulI)

EUM:	ECUMN_4820(sulI)

ELO:	EC042_4095(sulI)

ELN:	NRG857_30104

SEM:	STMDT12_C39260 STMDT12_L00620

SEND:

DT104_38581 DT104_38671

SENI:

CY43_20070 CY43_20120

SEC:	SCH_034(sulI)

SEH:	SeHA_C1582(folP)

SENH:

CFSAN002069_23160

SEE:	SNSL254_p_0039 SNSL254_p_0151(sul1)

SENN:

SN31241_6920

SALZ:

EOS98_23500(sul1)

ECLE:

ECNIH2_24610 ECNIH2_24645 ECNIH2_24930 ECNIH2_24945 ECNIH2_25870

ECLY:

LI62_012700 LI62_012780 LI62_012805

ECLZ:

LI64_22040 LI64_22080

EHM:	AB284_00820

KPN:	KPN_pKPN5p08200(sul)

KPM:	KPHS_p300670

KPH:	KPNIH24_17315 KPNIH24_26880

KPZ:	KPNIH27_26420 KPNIH27_26455 KPNIH27_26725

KPW:	KPNIH30_26940

KPG:	KPNIH32_28365

KPC:	KPNIH10_10980 KPNIH10_26715

KPX:	PMK1_ndm00223(folP)

KPB:	FH42_26780 FH42_26810

KPNE:

KU54_01525

KPNU:

LI86_15190 LI86_26850

KOE:	A225_1942 A225_NDM1p0130 A225_R1p0445 A225_R1p0755

KOK:	KONIH1_31140 KONIH1_31155 KONIH1_31195

KOC:	AB185_00185 AB185_01240 AB185_02730 AB185_03270

KQU:	AVR78_27130

EAR:

CCG28767

KLW:	DA718_21640(sul1) DA718_21670(sul1)

KGR:	JJJ10_28295(sul1) JJJ10_29155(sul1)

KPAS:

LUW96_29420(sul1) LUW96_29455(sul1)

CFD:	CFNIH1_06115 CFNIH1_25715 CFNIH1_25750 CFNIH1_26040 CFNIH1_26055

CFQ:	C2U38_21245

CSED:

JY391_23200(sul1) JY391_23220(sul1)

CFAR:

CI104_19160 CI104_25635 CI104_25685 CI104_25715 CI104_26840

CIE:	AN232_27630 AN232_29255

CITZ:

E4Z61_00240

CIX:	M4I31_16765(sul1)

KAS:	KATP_49740(sul1_1) KATP_49900(sul1_2)

LEI:	C2U54_25000 C2U54_26515 C2U54_26535

LEH:	C3F35_26130 C3F35_26150

YRE:	HEC60_24090

KIN:	AB182_00485 AB182_02790 AB182_03110

PDZ:	HHA33_25980(sul1)

METY:

MRY16398_p20100(sulI)

PVJ:	LMA04_21350(sul1) LMA04_22060(sul1) LMA04_22170(sul1)

EBC:	C2U52_01340 C2U52_01390 C2U52_01435

SMAR:

SM39_pSMC1_36(sulI1) SM39_pSMC1_47(sulI2)

PANT:

PSNIH1_20560 PSNIH1_20575

PANP:

PSNIH2_20735 PSNIH2_21675 PSNIH2_21690

PER:	LAC65_02015(sul1)

PCOL:

F1325_16210 F1325_16230

PCIB:

F9282_16490 F9282_19495(sul1) F9282_19530(sul1) F9282_19590(sul1)

PTHA:

OI982_21560(sul1)

PRG:	RB151_017570(folP_2)

PRQ:	CYG50_00345(sul1) CYG50_00650(folP) CYG50_12770(sul1) CYG50_12845(sul1)

PVC:	G3341_20165(sul1)

PHAG:

PZ638_20775(sul1) PZ638_21145

BTO:

WQG_1020

BTRH:

F543_22840

BTRA:

F544_3080

PMEX:

H4W19_04330(sul1)

VCF:	IR04_08305

VCE:	Vch1786_I0080

VCQ:	EN18_05235 EN18_05770 EN18_05795 EN18_06305 EN18_06355

VCJ:	VCD_003741

VNL:	D3H41_03115

PAP:	PSPA7_5341

PNC:	NCGM2_1761(sul1)

PAEB:

NCGM1900_1409(sulI) NCGM1900_3682(sulI) NCGM1900_3710(sulI)

PAEU:

BN889_07008

PPUH:

B479_26829 B479_26969

PPUD:

DW66_3632 DW66_3789

PALD:

LU682_024165(sul1) LU682_024215(folP)

PSEM:

TO66_31810

PTW:	TUM18999_61440

PJU:	L1P09_08565(sul1) L1P09_12625(sul1) L1P09_12670(folP) L1P09_25425(folP) L1P09_25560(sul1)

PTRL:

OU419_14265(sul1)

DCE:	O6P33_04385(sul1) O6P33_04490

PBAU:

OS670_08290(sul1) OS670_08335(sul1) OS670_12150(sul1) OS670_12195(sul1) OS670_20855(sul1) OS670_20920(sul1)

ABY:	ABAYE3568(sulI) ABAYE3612(sulI) ABAYE3616

ABC:	ACICU_00228

ABN:	AB57_0294(sul1) AB57_06260(sul1)

ABX:

ABK1_1142

ABZ:	ABZJ_01291(sul1) ABZJ_05060(sul1)

ABR:	ABTJ_01329 ABTJ_02581

ABD:	ABTW07_3887(sul1) ABTW07_3903(sul1)

ABH:

M3Q_2660

ABJ:	BJAB07104_p0091

ABAJ:

BJAB0868_p0102

AJO:	RZ95_17855 RZ95_17905

ADV:	DJ533_01165(sul1)

AVZ:	HWI77_18580(folP) HWI77_18625(sul1)

SALG:

BS332_22215

SHEJ:

MZ182_20580(sul1) MZ182_20625(sul1)

RHH:	E0Z06_12465 E0Z06_12485 E0Z06_12505 E0Z06_15060(sul1) E0Z06_15120(sul1) E0Z06_15150(sul1)

AHH:	RY45_02915

AAJ:	BOQ57_11190 BOQ57_11330

ASA:	ASA_P4G098(sul1)

AEA:	C2U39_10260 C2U39_22045 C2U39_23860 C2U39_23885

AES:	C2U30_02800

ASIM:

FE240_15665 FE240_15720(sul1)

PAND:

DRB87_20560(folP) DRB87_20600

PUS:	CKA81_11640(folP) CKA81_11700

AFA:	UZ73_19170

AAMM:

FE795_09125(sul1)

NARM:

N7E01_00020 N7E01_00040 N7E01_05295(folP) N7E01_05370(sul1)

CKE:	B5M06_08265

COF:	FOZ74_01875(sul1)

CRJ:	QMY55_04440(folP) QMY55_12310(folP) QMY55_12390(sul1)

HYB:

Q5W_18235

DIH:	G7047_30085(sul1) G7047_30155(folP)

SIMP:

C6571_18330

MELA:

C6568_16805

MJE:	LVC68_09465(sul1) LVC68_09510(folP)

THU:	AC731_003645

TAK:	Tharo_3439

BND:	KWG56_14235(sul1)

RHP:	LPB142_15560

PALP:

JHW40_14880(sul1)

SINA:

KNJ79_00025(sul1)

SPHD:

HY78_25150

SPHM:

G432_20800

SPHF:

DM480_17815

SLAN:

GV829_08800(sul1)

SAT:

SYN_02578

CDI:

DIP1948

CDB:	CDBH8_0910(sul1) CDBH8_2293(sulI)

CPRP:

I6I69_04540(sul1)

CHAD:

CHAD_02625(folP1)

CPYR:

CYJ47_11215(sul1)

MLIQ:

NMQ05_12940(sul1)

LARI:

KI794_14575(sul1)

GPR:	JQN66_17940(sul1) JQN66_18115(sul1)

GMY:	XH9_09410(sul1)

NAE:	BHE16_08510

TFL:	RPIT_14665

STUC:

G5S47_08120(sul1)

GHM:	CJ187_008105(sul1)

LBI:	LEPBI_I3239(sulI)

LBF:	LBF_3127(folP)

LAJ:	A0128_00250

DIN:	Selin_0011

AG:	CAO82704(sul1)

» show all

Reference

PMID:21564142

Authors

Partridge SR

Title

Analysis of antibiotic resistance regions in Gram-negative bacteria.

Journal

FEMS Microbiol Rev 35:820-55 (2011)
DOI:10.1111/j.1574-6976.2011.00277.x

Sequence

[paeb:NCGM1900_1409]

LinkDB

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