KEGG   ORTHOLOGY: K19099
Entry
K19099            Tight     KO                                     
Symbol
blaGIM
Name
metallo-beta-lactamase class B GIM [EC:3.5.2.6]
Pathway
map01501  beta-Lactam resistance
Module
M00851  Carbapenem resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K19099  blaGIM; metallo-beta-lactamase class B GIM
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K19099  blaGIM; metallo-beta-lactamase class B GIM
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.6  beta-lactamase
     K19099  blaGIM; metallo-beta-lactamase class B GIM
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  beta-Lactamase genes
   Class B [MT]
    K19099  blaGIM; metallo-beta-lactamase class B GIM
Antimicrobial resistance: KEGG signatures [br01600.html]
 Signature KOs for antimicrobial resistance
  K19099
Other DBs
COG: COG0491
GO: 0008800
Genes
AG: AIY26289(GIM-2) CAF05908(GIM-1)
Reference
PMID:15561840
  Authors
Castanheira M, Toleman MA, Jones RN, Schmidt FJ, Walsh TR
  Title
Molecular characterization of a beta-lactamase gene, blaGIM-1, encoding a new subclass of metallo-beta-lactamase.
  Journal
Antimicrob Agents Chemother 48:4654-61 (2004)
DOI:10.1128/AAC.48.12.4654-4661.2004
  Sequence
[ag:CAF05908]
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