KEGG   ORTHOLOGY: K19104
Entry
K19104                      KO                                     
Symbol
nat
Name
isonocardicin synthase [EC:2.5.1.38]
Pathway
map00261  Monobactam biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00736  Nocardicin A biosynthesis, L-pHPG + arginine + serine => nocardicin A
Reaction
R03072  S-adenosyl-L-methionine:nocardicin-E 3-amino-3-carboxypropyltransferase
R10881  S-adenosyl-L-methionine:nocardicin-G 3-amino-3-carboxypropyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    K19104  nat; isonocardicin synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K19104  nat; isonocardicin synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.38  isonocardicin synthase
     K19104  nat; isonocardicin synthase
Polyketide biosynthesis proteins [BR:ko01008]
 Nonribosomal peptide tailoring proteins
  Others
   K19104  nat; isonocardicin synthase
Other DBs
GO: 0050007
Genes
PTRT: HU722_0017545
PORY: EJA05_18815
PWY: HU734_009855
BURK: DM992_25505
AMI: Amir_4587
KUT: JJ691_05160
ACTI: UA75_15395
ACAD: UA74_14825
ACTA: C1701_23395
AG: AAD46393(nat)
Reference
PMID:9804844
  Authors
Reeve AM, Breazeale SD, Townsend CA
  Title
Purification, characterization, and cloning of an S-adenosylmethionine-dependent 3-amino-3-carboxypropyltransferase in nocardicin biosynthesis.
  Journal
J Biol Chem 273:30695-703 (1998)
DOI:10.1074/jbc.273.46.30695
Reference
  Authors
Gunsior M, Breazeale SD, Lind AJ, Ravel J, Janc JW, Townsend CA
  Title
The biosynthetic gene cluster for a monocyclic beta-lactam antibiotic, nocardicin A.
  Journal
Chem Biol 11:927-38 (2004)
DOI:10.1016/j.chembiol.2004.04.012
  Sequence
LinkDB

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