KEGG   ORTHOLOGY: K19215
Entry
K19215            Tight     KO                                     
Symbol
blaACT_MIR
Name
beta-lactamase class C ACT/MIR [EC:3.5.2.6]
Pathway
map01501  beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K19215  blaACT_MIR; beta-lactamase class C ACT/MIR
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K19215  blaACT_MIR; beta-lactamase class C ACT/MIR
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.6  beta-lactamase
     K19215  blaACT_MIR; beta-lactamase class C ACT/MIR
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  beta-Lactamase genes
   Class C [MT]
    K19215  blaACT_MIR; beta-lactamase class C ACT/MIR
Antimicrobial resistance: KEGG signatures [br01600.html]
 Signature KOs for antimicrobial resistance
  K19215
Other DBs
COG: COG1680
GO: 0008800
Genes
ENC: ECL_00553(ampC)
ENL: A3UG_02005(ampC)
ECLG: EC036_03780
ECLE: ECNIH2_02940
ECLN: ECNIH4_20875
ECLI: ECNIH5_02160
ECLX: LI66_02000
ECLY: LI62_02455
ECLZ: LI64_02135
ECLO: ENC_42520
EHM: AB284_23080
EXF: BFV63_01975
ECLA: ECNIH3_02160
ECLC: ECR091_02150
EAU: DI57_16555
EKB: BFV64_01630
ENO: ECENHK_01980(ampC)
EEC: EcWSU1_00354(ampC)
ELG: BH714_16435
ECAN: CWI88_20280
ERN: BFV67_01950
ECLS: LI67_003020
ECHG: FY206_02495
ESH: C1N69_01950
EPT: HWQ17_10540(blaACT)
EAS: Entas_0373
ENX: NI40_002070
LNI: CWR52_10520(ampC)
EBG: FAI37_04630(blaACT)
END: A4308_00885
ENZ: G0034_01810(blaACT)
ENS: HWQ15_10455(blaACT)
ENK: LOC22_12815(blaACT)
EHU: D5067_0021125(blaACT)
EMOR: L6Y89_01780(blaACT)
ENB: ELK40_02705(ampC)
EQU: OM418_01925(blaACT)
EPU: QVH39_01915(blaACT)
KIE: NCTC12125_03325(ampC_2)
AG: AAC45086(ACT-1) AAD22636(MIR-1) ABL67017(ACT-3) ABN69112(MIR-4) ACJ05686(ACT-6) AEI70575(ACT-9) AFU25647(ACT-14) AFU25650(ACT-12) AFU25653(ACT-15) AGU38146(ACT-23) AHA80105(ACT-20) AHA80106(ACT-21) AHM76771(ACT-17) AHM76774(ACT-22) AHM76777(ACT-18) AHM76779(ACT-19) BAM34463(ACT-16) CCK86741(ACT-13) CDP41983(ACT-34)
 » show all
Reference
PMID:9055993
  Authors
Bradford PA, Urban C, Mariano N, Projan SJ, Rahal JJ, Bush K
  Title
Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the foss of an outer membrane protein.
  Journal
Antimicrob Agents Chemother 41:563-9 (1997)
DOI:10.1128/AAC.41.3.563
  Sequence
[ag:AAC45086]
Reference
PMID:1963529
  Authors
Papanicolaou GA, Medeiros AA, Jacoby GA
  Title
Novel plasmid-mediated beta-lactamase (MIR-1) conferring resistance to oxyimino- and alpha-methoxy beta-lactams in clinical isolates of Klebsiella pneumoniae.
  Journal
Antimicrob Agents Chemother 34:2200-9 (1990)
DOI:10.1128/AAC.34.11.2200
  Sequence
[ag:AAD22636]
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