KEGG   ORTHOLOGY: K19256
Entry
K19256                      KO                                     
Symbol
gC
Name
Simplexvirus envelope glycoprotein C
Pathway
map03266  Virion - Herpesvirus
map05168  Herpes simplex virus 1 infection
Network
nt06168  Herpes simplex virus 1 (HSV-1)
nt06513  Complement cascade
  Element
N00589  HSV gC to alternative pathway of complement cascade
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03266 Virion - Herpesvirus
    K19256  gC; Simplexvirus envelope glycoprotein C
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    K19256  gC; Simplexvirus envelope glycoprotein C
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K19256  gC; Simplexvirus envelope glycoprotein C
  09185 Viral protein families
   03200 Viral proteins
    K19256  gC; Simplexvirus envelope glycoprotein C
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Microbial pathogens
   K19256  gC; Simplexvirus envelope glycoprotein C
Viral proteins [BR:ko03200]
 dsDNA viruses
  Human herpes simplex virus 1/2
   K19256  gC; Simplexvirus envelope glycoprotein C
Virus entry [br03220.html]
 Viral entry protein - non-protein receptor interactions
  K19256
Virus entry: animal viruses [br03222.html]
 Entry protein - non-protein receptor interactions
  K19256
Genes
VG: 12413920(ORF16) 1487331(UL44) 1487439(UL44) 1487561(ORF16) 1487579(ORF16) 18533936(UL44) 19621689(UL44) 20194325(ORF16) 2703410(UL44) 2952505(UL44) 3190342(UL44) 3850227(UL44) 7070123(ORF16) 80532075(ORF16) 80532556(UL44) 80535082(UL44) 80535176(UL44) 80540232(UL44) 9829313(UL44)
Reference
  Authors
Reske A, Pollara G, Krummenacher C, Chain BM, Katz DR
  Title
Understanding HSV-1 entry glycoproteins.
  Journal
Rev Med Virol 17:205-15 (2007)
DOI:10.1002/rmv.531
Reference
  Authors
Livingston JR, Sutherland MR, Friedman HM, Pryzdial EL
  Title
Herpes simplex virus type 1-encoded glycoprotein C contributes to direct coagulation factor X-virus binding.
  Journal
Biochem J 393:529-35 (2006)
DOI:10.1042/BJ20051313
  Sequence
[vg:2703410]
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