KEGG   ORTHOLOGY: K19274
Entry
K19274            Tight     KO                                     
Symbol
aph3-VI
Name
aminoglycoside 3'-phosphotransferase VI [EC:2.7.1.95]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K19274  aph3-VI; aminoglycoside 3'-phosphotransferase VI
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.95  kanamycin kinase
     K19274  aph3-VI; aminoglycoside 3'-phosphotransferase VI
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  Aminoglycoside resistance genes
   O-Phosphotransferases
    K19274  aph3-VI; aminoglycoside 3'-phosphotransferase VI
Antimicrobial resistance: KEGG signatures [br01600.html]
 Signature KOs for antimicrobial resistance
  K19274
Other DBs
GO: 0008910
Genes
KPB: FH42_25875
PCIB: F9282_16450(aph(3')-VI)
PALD: LU682_024260
PJU: L1P09_08635
DCE: O6P33_04935
ABAB: BJAB0715_p0002
ABAZ: AGW27715.1
ANO: RR32_19120
AJO: RZ95_17955
ADV: DJ533_01225
ACUM: C9E88_015545(aph(3')-VI)
AGU: AS4_23160
ACHI: CDG60_00305(aph(3')-VI) CDG60_00550
APOT: MZO21_14195
AG: CAA30578(aph(3')-VIa) CAF29483(aph(3')-VIb)
 » show all
Reference
PMID:2846986
  Authors
Martin P, Jullien E, Courvalin P
  Title
Nucleotide sequence of Acinetobacter baumannii aphA-6 gene: evolutionary and functional implications of sequence homologies with nucleotide-binding proteins, kinases and other aminoglycoside-modifying enzymes.
  Journal
Mol Microbiol 2:615-25 (1988)
DOI:10.1111/j.1365-2958.1988.tb00070.x
  Sequence
[abab:BJAB0715_p0002]
Reference
PMID:8385262
  Authors
Shaw KJ, Rather PN, Hare RS, Miller GH
  Title
Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes.
  Journal
Microbiol Rev 57:138-63 (1993)
DOI:10.1128/mr.57.1.138-163.1993
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