KEGG   ORTHOLOGY: K19542
Entry
K19542            Tight     KO                                     
Symbol
otrB, tcr
Name
MFS transporter, DHA2 family, tetracycline/oxytetracycline resistance protein
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K19542  otrB, tcr; MFS transporter, DHA2 family, tetracycline/oxytetracycline resistance protein
   01504 Antimicrobial resistance genes
    K19542  otrB, tcr; MFS transporter, DHA2 family, tetracycline/oxytetracycline resistance protein
Transporters [BR:ko02000]
 Major facilitator superfamily (MFS)
  Drug transporters
   Drug:H+ antiporter-2 (14 spanner) (DHA2) family
    K19542  otrB, tcr; MFS transporter, DHA2 family, tetracycline/oxytetracycline resistance protein
Antimicrobial resistance genes [BR:ko01504]
 Gene variants
  Tetracycline resistance genes
   Transporters
    K19542  otrB, tcr; MFS transporter, DHA2 family, tetracycline/oxytetracycline resistance protein
Other DBs
COG: COG2814
TC: 2.A.1.3.29
Genes
SVR: CP971_23940(tcr3)
KAU: B6264_18515
AG: AAD04032(otr(B)) BAA07390(tcr)
Reference
PMID:9867793
  Authors
McMurry LM, Levy SB
  Title
Revised sequence of OtrB (tet347) tetracycline efflux protein from Streptomyces rimosus.
  Journal
Antimicrob Agents Chemother 42:3050 (1998)
DOI:10.1128/AAC.42.11.3050
  Sequence
[ag:AAD04032]
Reference
PMID:8534971
  Authors
Dairi T, Aisaka K, Katsumata R, Hasegawa M
  Title
A self-defense gene homologous to tetracycline effluxing gene essential for antibiotic production in Streptomyces aureofaciens.
  Journal
Biosci Biotechnol Biochem 59:1835-41 (1995)
DOI:10.1271/bbb.59.1835
  Sequence
[ag:BAA07390]
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