KEGG   ORTHOLOGY: K20565
Entry
K20565                      KO                                     
Symbol
neoG, neoQ
Name
paromamine 6'-oxidase / 6'''-hydroxyneomycin C oxidase [EC:1.1.3.43 1.1.3.44]
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R08896  paromamine:oxygen 6'-oxidoreductase
R08902  6'''-deamino-6'''-hydroxyneomycin-C:oxygen 6'''-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K20565  neoG, neoQ; paromamine 6'-oxidase / 6'''-hydroxyneomycin C oxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.3  With oxygen as acceptor
    1.1.3.43  paromamine 6'-oxidase
     K20565  neoG, neoQ; paromamine 6'-oxidase / 6'''-hydroxyneomycin C oxidase
    1.1.3.44  6'''-hydroxyneomycin C oxidase
     K20565  neoG, neoQ; paromamine 6'-oxidase / 6'''-hydroxyneomycin C oxidase
Other DBs
COG: COG2303
Genes
SRN: A4G23_05124(neoG)
SFB: CP974_27345
DMAT: Dmats_04980
AG: BAD95824(neoG)
Reference
  Authors
Kudo F, Yamamoto Y, Yokoyama K, Eguchi T, Kakinuma K
  Title
Biosynthesis of 2-deoxystreptamine by three crucial enzymes in Streptomyces fradiae NBRC 12773.
  Journal
J Antibiot (Tokyo) 58:766-74 (2005)
DOI:10.1038/ja.2005.104
  Sequence
Reference
  Authors
Huang F, Spiteller D, Koorbanally NA, Li Y, Llewellyn NM, Spencer JB
  Title
Elaboration of neosamine rings in the biosynthesis of neomycin and butirosin.
  Journal
Chembiochem 8:283-8 (2007)
DOI:10.1002/cbic.200600371
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