KEGG   ORTHOLOGY: K20567
Entry
K20567                      KO                                     
Symbol
neoN
Name
neamine transaminase / neomycin C transaminase [EC:2.6.1.93 2.6.1.95]
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R08897  neamine:2-oxoglutarate aminotransferase
R08903  2-oxoglutarate:neomycin-C aminotransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K20567  neoN; neamine transaminase / neomycin C transaminase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.93  neamine transaminase
     K20567  neoN; neamine transaminase / neomycin C transaminase
    2.6.1.95  neomycin C transaminase
     K20567  neoN; neamine transaminase / neomycin C transaminase
Other DBs
COG: COG0001
Genes
SRN: A4G23_05117(neoN)
SFB: CP974_27310
AG: BAD95831(neoN)
Reference
  Authors
Kudo F, Yamamoto Y, Yokoyama K, Eguchi T, Kakinuma K
  Title
Biosynthesis of 2-deoxystreptamine by three crucial enzymes in Streptomyces fradiae NBRC 12773.
  Journal
J Antibiot (Tokyo) 58:766-74 (2005)
DOI:10.1038/ja.2005.104
  Sequence
Reference
  Authors
Huang F, Spiteller D, Koorbanally NA, Li Y, Llewellyn NM, Spencer JB
  Title
Elaboration of neosamine rings in the biosynthesis of neomycin and butirosin.
  Journal
Chembiochem 8:283-8 (2007)
DOI:10.1002/cbic.200600371
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