KEGG   ORTHOLOGY: K20579
Entry
K20579            Tight     KO                                     
Symbol
tobZ
Name
nebramycin 5' synthase [EC:6.1.2.2]
Pathway
map00524  Neomycin, kanamycin and gentamicin biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R10767  tobramycin:carbamoyl-phosphate ligase (AMP,phosphate-forming)
R10768  kanamycin-A:carbamoyl-phosphate ligase (AMP,phosphate-forming)
R11279  kanamycin-B:carbamoyl-phosphate ligase (AMP,phosphate-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K20579  tobZ; nebramycin 5' synthase
Enzymes [BR:ko01000]
 6. Ligases
  6.1  Forming carbon-oxygen bonds
   6.1.2  acid-alcohol ligases (ester synthases)
    6.1.2.2  nebramycin 5' synthase
     K20579  tobZ; nebramycin 5' synthase
Other DBs
COG: COG2192
Genes
AG: CAE22473(tobZ)
Reference
PMID:22383337
  Authors
Parthier C, Gorlich S, Jaenecke F, Breithaupt C, Brauer U, Fandrich U, Clausnitzer D, Wehmeier UF, Bottcher C, Scheel D, Stubbs MT
  Title
The O-carbamoyltransferase TobZ catalyzes an ancient enzymatic reaction.
  Journal
Angew Chem Int Ed Engl 51:4046-52 (2012)
DOI:10.1002/anie.201108896
  Sequence
[ag:CAE22473]
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