KEGG   ORTHOLOGY: K21049
Entry
K21049                      KO                                     
Symbol
UL141
Name
Cytomegalovirus protein UL141
Pathway
map04061  Viral protein interaction with cytokine and cytokine receptor
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04061 Viral protein interaction with cytokine and cytokine receptor
    K21049  UL141; Cytomegalovirus protein UL141
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K21049  UL141; Cytomegalovirus protein UL141
Viral proteins [BR:ko03200]
 dsDNA viruses
  Human cytomegalovirus (Human herpesvirus 5)
   K21049  UL141; Cytomegalovirus protein UL141
Viral network perturbations [br03223.html]
 Cytokine-cytokine receptor interaction
  K21049
Genes
VG: 11294192(KM472_gp199) 24284827(AA805_gp22) 25026537(UL141) 2952673(grh164) 3077418(UL141) 30855136(BWV06_gp124) 935461(UL141)
Reference
  Authors
Smith W, Tomasec P, Aicheler R, Loewendorf A, Nemcovicova I, Wang EC, Stanton RJ, Macauley M, Norris P, Willen L, Ruckova E, Nomoto A, Schneider P, Hahn G, Zajonc DM, Ware CF, Wilkinson GW, Benedict CA
  Title
Human cytomegalovirus glycoprotein UL141 targets the TRAIL death receptors to thwart host innate antiviral defenses.
  Journal
Cell Host Microbe 13:324-35 (2013)
DOI:10.1016/j.chom.2013.02.003
  Sequence
[vg:3077418]
Reference
  Authors
Prod'homme V, Sugrue DM, Stanton RJ, Nomoto A, Davies J, Rickards CR, Cochrane D, Moore M, Wilkinson GW, Tomasec P
  Title
Human cytomegalovirus UL141 promotes efficient downregulation of the natural killer cell activating ligand CD112.
  Journal
J Gen Virol 91:2034-9 (2010)
DOI:10.1099/vir.0.021931-0
  Sequence
[vg:3077418]
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