KEGG   ORTHOLOGY: K21146
Entry
K21146                      KO                                     
Symbol
CYP105A1
Name
vitamin D 1,25-hydroxylase [EC:1.14.15.22]
Pathway
map00100  Steroid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R11458  calciol,ferredoxin:oxygen oxidoreductase (1,25-hydroxylating)
R11459  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    K21146  CYP105A1; vitamin D 1,25-hydroxylase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K21146  CYP105A1; vitamin D 1,25-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.22  vitamin D 1,25-hydroxylase
     K21146  CYP105A1; vitamin D 1,25-hydroxylase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, bacteria type
  CYP105 family
   K21146  CYP105A1; vitamin D 1,25-hydroxylase
Other DBs
COG: COG2124
Genes
NBR: O3I_016665
NOZ: DMB37_03450
SSX: SACTE_6300
STRE: GZL_08768
SNR: SNOUR_39820
SALU: DC74_467
SALL: SAZ_02815
SGD: ELQ87_03740
SRIM: CP984_00750
SHUN: DWB77_06762
AG: AAA26823(CYP105A1)
 » show all
Reference
PMID:2345149
  Authors
Omer CA, Lenstra R, Litle PJ, Dean C, Tepperman JM, Leto KJ, Romesser JA, O'Keefe DP
  Title
Genes for two herbicide-inducible cytochromes P-450 from Streptomyces griseolus.
  Journal
J Bacteriol 172:3335-45 (1990)
DOI:10.1128/JB.172.6.3335-3345.1990
  Sequence
Reference
  Authors
Sawada N, Sakaki T, Yoneda S, Kusudo T, Shinkyo R, Ohta M, Inouye K
  Title
Conversion of vitamin D3 to 1alpha,25-dihydroxyvitamin D3 by Streptomyces griseolus cytochrome P450SU-1.
  Journal
Biochem Biophys Res Commun 320:156-64 (2004)
DOI:10.1016/j.bbrc.2004.05.140
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