KEGG   ORTHOLOGY: K21148
Entry
K21148                      KO                                     
Symbol
cysM
Name
[CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase [EC:2.5.1.113]
Pathway
map04122  Sulfur relay system
Reaction
R10610  O-phospho-L-serine:thiocarboxy-[sulfur-carrier protein] 2-amino-2-carboxyethyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04122 Sulfur relay system
    K21148  cysM; [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.113  [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase
     K21148  cysM; [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase
Other DBs
COG: COG0031
Genes
BEX: A11Q_332
ERZ: ER308_03705
EUZ: DVS28_a1371
MTU: Rv1336(cysM)
MTV: RVBD_1336
MTC: MT1377(cysM)
MRA: MRA_1344(cysM)
MTF: TBFG_11366
MTB: TBMG_02642
MTK: TBSG_02656
MTZ: TBXG_002622
MTG: MRGA327_08375
MTE: CCDC5079_1237
MTUR: CFBS_1421(cysM)
MTL: CCDC5180_1228
MTO: MTCTRI2_1373(cysM)
MTD: UDA_1336(cysM)
MTN: ERDMAN_1496(cysM)
MTJ: J112_07205
MTUB: MT7199_1368
MTUC: J113_09305
MTUE: J114_07185
MTX: M943_07005
MTUL: TBHG_01323
MTUT: HKBT1_1420(cysM)
MTUU: HKBT2_1426(cysM)
MTQ: HKBS1_1424(cysM)
MBO: BQ2027_MB1371(cysM)
MBB: BCG_1398(cysM)
MBT: JTY_1372(cysM)
MBM: BCGMEX_1370(cysM)
MBK: K60_014350
MBX: BCGT_1171
MAF: MAF_13600(cysM)
MMIC: RN08_1495
MCE: MCAN_13541(cysM)
MCQ: BN44_11502(cysM)
MCV: BN43_30435(cysM)
MCX: BN42_21245(cysM)
MCZ: BN45_30418(cysM)
MORY: MO_001435(cysM)
MSA: Mycsm_04617
MUL: MUL_0242(cysM)
MMI: MMAR_4629(cysM)
MMAE: MMARE11_44530(cysM)
MLI: MULP_04839(cysM)
MPSE: MPSD_47870(cysM)
MSHO: MSHO_22410(cysM)
MMC: Mmcs_3848
MKM: Mkms_3922
MJL: Mjls_3834
MKN: MKAN_06205
MYV: G155_21135(cysM)
MYE: AB431_22045(cysM)
MHAD: B586_08340(cysM)
MDX: BTO20_10025(cysM)
MFJ: MFLOJ_50330(cysM)
MXE: MYXE_16650(cysM)
MNV: MNVI_03280(cysM)
MBAI: MB901379_03526(cysM)
MHEK: JMUB5695_01732(cysM)
MGAU: MGALJ_26840(cysM)
MLJ: MLAC_10040(cysM)
MBRD: MBRA_31190(cysM)
MSHJ: MSHI_05610(cysM)
MMAM: K3U93_17360
MSPG: F6B93_16225
MOT: LTS72_05035
MADI: A7U43_10885(cysM)
MSM: MSMEG_4905(cysM)
MSG: MSMEI_4778
MSB: LJ00_24255(cysM)
MSN: LI99_24260(cysM)
MSH: LI98_24265(cysM)
MVA: Mvan_4291
MGI: Mflv_2354
MSP: Mspyr1_17870
MCB: Mycch_3736
MNE: D174_20015(cysM)
MYN: MyAD_19640(cysM)
MFT: XA26_43140
MPHL: MPHLCCUG_03882(cysM)
MVQ: MYVA_4106(cysM)
MRH: MycrhN_3866
MTHN: 4412656_03139(cysM)
MHAS: MHAS_02665(cysM)
MDU: MDUV_03800(cysM)
MDR: MDOR_27070(cysM)
MAUU: NCTC10437_04035(cysM)
MMOR: MMOR_22560(cysM)
MALV: MALV_51390(cysM)
MTY: MTOK_00950
MPSC: MPSYJ_25300(cysM)
MARZ: MARA_57190(cysM)
MGAD: MGAD_55760(cysM)
MHEV: MHEL_06120(cysM)
MSAR: MSAR_30230
MANY: MANY_22430(cysM)
MPOF: MPOR_43880(cysM)
MMAT: MMAGJ_01740(cysM)
MBOK: MBOE_30700(cysM)
MSEI: MSEDJ_51670
MFLV: NCTC10271_01413(cysM)
MCEE: MCEL_47020(cysM)
MMON: EWR22_19700
MGO: AFA91_15975(cysM)
MHOL: K3U96_07710
MSEN: K3U95_08760
MRF: MJO55_19470
MDF: K0O62_20960
MGRO: FZ046_24910
MKR: MKOR_08390
MPAK: MIU77_08560
MAB: MAB_1480
MMV: MYCMA_0803
MABB: MASS_1472
MABL: MMASJCM_1499
MCHE: BB28_07370(cysM)
MIZ: BAB75_07995(cysM)
MSTE: MSTE_01457
MSAO: MYCSP_06580(cysM)
MSAL: DSM43276_01343(cysM)
ASD: AS9A_1109
NFA: NFA_10910(cysM)
NFR: ERS450000_03020(cysM_1)
NCY: NOCYR_1176(cysM)
NBR: O3I_006480
NNO: NONO_c12910(cysM) NONO_c40660
NSL: BOX37_25295(cysM)
NSR: NS506_04798(cysM) NS506_07155
NTP: CRH09_07265(cysM)
NOZ: DMB37_27415(cysM)
NOD: FOH10_24795
NAH: F5544_07735 F5544_21065
NAD: NCTC11293_01987(cysM_1)
NWL: NWFMUON74_59190
NIE: KV110_07070 KV110_20310
NTC: KHQ06_37850
NHU: H0264_37005
NYA: LTV02_09555 LTV02_36215
NGP: LTT66_05890
NSPU: IFM12276_51440(cysM)
NYU: D7D52_11165
RHA: RHA1_ro01436(cysM)
ROP: ROP_11430(cysM) ROP_11450(cysM)
ROA: Pd630_LPD05558 Pd630_LPD05560
RHW: BFN03_11000(cysM)
RTM: G4H71_02325
RKO: JWS14_07380 JWS14_07390
ROZ: CBI38_10795(cysM)
RPSK: JWS13_38790 JWS13_38800
GBR: Gbro_1967
GPO: GPOL_c18620(cysM)
GOR: KTR9_1899
GOQ: ACH46_07410(cysM)
GTA: BCM27_10205(cysM)
GRU: GCWB2_09585(cysM2)
GOM: D7316_00476(cysM)
GAV: C5O27_18170(cysM)
GOD: GKZ92_09190
GAM: GII34_08840
GPD: GII33_08230
GJI: H1R19_09475
GOI: LK459_00855
GHN: MVF96_09600
GAMI: IHQ52_12480
GMG: NWF22_19885
SPIN: KV203_05210
TPR: Tpau_1291
TSM: ASU32_07345(cysM)
TPUL: TPB0596_32920
TSD: MTP03_13750
SCO: SCO2910(SCE19A.10c)
SALB: XNR_1784
SMA: SAVERM_5164(cysM2)
SGR: SGR_4632
SGB: WQO_12370(cysM)
SFI: SFUL_2504
SANL: KZO11_12670
SGRF: SGFS_048310
SCYE: R2B67_23265
SCB: SCAB_56551 SCAB_86101
SSX: SACTE_0751 SACTE_2387
SVL: Strvi_3366 Strvi_8262
SHY: SHJG_4386
SHO: SHJGH_4149
SRC: M271_30300
SMAL: SMALA_2974
SSOI: I1A49_18795
SFA: Sfla_3986
SBH: SBI_02244(cysM2) SBI_06684(cysM3)
SVE: SVEN_2662
SDV: BN159_5378(cysM)
SALS: SLNWT_2450
STRP: F750_2736
SCI: B446_15210
SLV: SLIV_23140(cysM)
SGU: SGLAU_13170(cysM)
SVT: SVTN_14255(cysM)
STRE: GZL_01160 GZL_05560
SCW: TU94_12665(cysM)
SLD: T261_5208
SLC: SL103_00750 SL103_04775(cysM)
SXI: SXIM_39020
STRM: M444_13795(cysM)
STRC: AA958_10735(cysM)
SAMB: SAM23877_0667 SAM23877_2947(cysM)
SPRI: SPRI_4639
SCZ: ABE83_23465(cysM)
SCX: AS200_27885(cysM)
SRW: TUE45_03502(cysM)
STRF: ASR50_01840 ASR50_14080(cysM)
SLE: sle_43610(sle_43610)
SRN: A4G23_01928(cysM_1) A4G23_04707(cysK)
SPAV: Spa2297_12450(cysM)
STRT: A8713_11700(cysM)
SCLF: BB341_18215(cysM)
SGS: AVL59_42290(cysM)
STSI: A4E84_15310(cysM)
SKY: D0C37_10680
SALW: CP975_13075
SGM: GCM10017557_51680 GCM10017557_72480
SCAD: DN051_24120(cysM)
SPHW: NFX46_35390
SLS: SLINC_3312
SNR: SNOUR_25975
SALU: DC74_3343
SALL: SAZ_17810
SPLU: LK06_011185(cysM)
STRD: NI25_24205(cysM)
SNW: BBN63_22260(cysM)
SAUO: BV401_18535(cysM)
SSIA: A7J05_22375(cysM)
SVU: B1H20_11625(cysM)
SPUN: BFF78_25945(cysM)
SGV: B1H19_16130(cysM)
SLAU: SLA_2642
SALF: SMD44_03215(cysM)
SALJ: SMD11_4299(cysM)
SLX: SLAV_23445(cysM2)
STRO: STRMOE7_15100(cysM) STRMOE7_19095
SFK: KY5_3048c
SNZ: DC008_12820(cysM)
SGE: DWG14_05208(cysM)
SRJ: SRO_4572
SLK: SLUN_14885(cysM)
SDX: C4B68_25130(cysM)
SGD: ELQ87_07590 ELQ87_24040
SQZ: FQU76_10805
SCYA: EJ357_17420
SAST: CD934_20820(cysM) CD934_30860
SNQ: CP978_04895 CP978_13425
STIR: DDW44_09560(cysM)
SKA: CP970_27280
SGZ: C0216_26580(cysM)
SVN: CP980_02895 CP980_21065
SNK: CP967_21745
SHAW: CEB94_15840(cysM)
SRK: FGW37_12000
SFIC: EIZ62_20880 EIZ62_22970
SGAL: CP966_13855
SSPO: DDQ41_07955(cysM) DDQ41_28910
SVR: CP971_21215
SPAD: DVK44_10510
SFY: GFH48_25075
SAQU: EJC51_19845
SGF: HEP81_04911
SCAV: CVT27_11085(cysM)
SSEO: D0Z67_10705
SBY: H7H31_22965
SRIM: CP984_25625
SSUB: CP968_20865
SPHV: F9278_17455
SCIN: CP977_12945
SFUG: CNQ36_13190(cysM)
SPAC: B1H29_22940(cysM) B1H29_35220
STSU: B7R87_10460(cysM)
SCHA: CP983_26745 CP983_38750
SGX: H4W23_15420
SCOE: CP976_16985
SBAT: G4Z16_22140
SSPB: CP982_17220
SNF: JYK04_03503(cysM)
SPLA: CP981_14760
SBRO: GQF42_18205
STUI: GCM10017668_26010
SATA: C5746_15780(cysM)
SCHF: IPT68_14110
SHUN: DWB77_04794(cysM)
SHAR: HUT13_19500
SCYG: S1361_15730(cysM2)
SFEU: IM697_06540
SLIA: HA039_22145
SDW: K7C20_13810
SVD: CP969_15615
SCAL: I6J39_11825
SAUH: SU9_012335
SFB: CP974_10730 CP974_25235
SMOB: J7W19_11805
SPRA: CP972_13910
SPEU: CGZ69_13080(cysM)
SROI: IAG44_25555
SXN: IAG42_21845
SGJ: IAG43_11625
SHK: J2N69_13285
SANU: K7396_22805
STRY: EQG64_11625
SDD: D9753_21950
SACT: DMT42_15225(cysM)
SMAO: CAG99_09815 CAG99_17795(cysM)
SGOB: test1122_07890
SINE: KI385_17825
SLF: JEQ17_29055
SDEC: L3078_17665
SAOV: G3H79_23265
SDUR: M4V62_26300
SYAN: NRK68_12875
SRUG: F0345_19230
SAKB: K1J60_27360
STAA: LDH80_25010
SNIG: HEK616_04610
SVIO: HWN34_09610
SCAE: IHE65_27785
STUB: MMF93_12465
SSPN: LXH13_25185
SCIR: STRCI_003260
SXT: KPP03845_103035(cysM_2)
SLON: LGI35_18890
SDRZ: NEH16_20045
STUD: STRTU_004481
STEE: F3L20_18700 F3L20_27805
SENG: OJ254_13810
SGK: PET44_12495
SANT: QR300_26575
SYUN: MOV08_26210
SARG: HKX69_21325
SJN: RI060_26290
SCYN: N8I84_16010
SOV: QZH56_23035
SFIY: F0344_22900
SHAU: K9S39_28090 K9S39_40135
SKG: KJK29_23490
SCOA: QU709_26505
SLAI: P8A22_24730
SROC: RGF97_21130
SFP: QUY26_24815
SCHG: NRO40_10815 NRO40_23925
STTN: BSL84_12465(cysM)
SINN: ABB07_23415(cysM)
STRZ: OYE22_22115
SCAY: PYS65_02910 PYS65_22435
SCT: SCAT_1941(cysM)
SCY: SCATT_19320
KSK: KSE_28250(cysM)
KAB: B7C62_11275(cysM)
KAU: B6264_15885(cysM)
KIT: CFP65_2632
KIS: HUT16_12130
STRI: C7M71_010095 C7M71_029405
YIA: LO772_22060
STRH: GXP74_06455
ABRY: NYE86_05640 NYE86_17640
AGLA: OIE69_24910
MPH: MLP_38890(cysM)
MIK: FOE78_07660
MICG: GJV80_00370
NCA: Noca_1312
NDK: I601_2313(cysM)
NOY: EXE57_17285
NOI: FCL41_04360
NOO: FE634_04935
NDP: E2C04_05115
NSN: EXE58_02090
NBE: Back2_09640
NANO: G5V58_03455
NMES: H9L09_03400
NARO: CFH99_07565(cysM)
NPI: G7071_00050
NAQU: ENKNEFLB_03479(cysM)
NRO: K8W59_14820
NOQ: LN652_07300
NCQ: K6T13_12975
NPC: KUV85_00960
NPS: KRR39_13930
NMAR: HPC71_05875
NFC: KG111_13255
PSIM: KR76_08150
AER: AERYTH_05540(cysM)
AEZ: C3E78_04875(cysM)
AEB: C6I20_10850(cysM)
AEF: GEV26_04685
ASEZ: H9L21_11945
ADB: NP095_11905
AWN: NQV15_04905
MUZ: H4N58_14990
SGRG: L0C25_16625
NBT: KLP28_10140
KFL: Kfla_1841
KQI: F1D05_29010
KSL: OG809_20975
TFU: Tfu_2368
THAO: NI17_014740
TALX: FOF52_12040
NDA: Ndas_0383
NAL: B005_3251(cysM)
NGV: CDO52_22910(cysM)
NEX: NE857_08160
NAKE: KGD83_23905
NCG: KGD84_25545
STRR: EKD16_05490(cysM)
SNAH: OUQ99_25365
SAIU: J4H86_11110
TCU: Tcur_3871
ACTW: F7P10_27500
AGRA: AGRA3207_002605
AMAZ: LUW76_35210
ACIR: OG979_25640
SPIQ: OHA34_16495
ACTQ: OG417_10115
SRO: Sros_1728
NOA: BKM31_36130(cysM)
NOW: GBF35_08935
NCX: Nocox_08295(cysM)
NGN: LCN96_09295
NFS: OIE67_37570
TBI: Tbis_0938
MHAI: OHB01_20170
FRA: Francci3_0868
FAL: FRAAL1500(cysM)
FRE: Franean1_5652
FSY: FsymDg_1244
FRI: FraEuI1c_5851
ACE: Acel_1687
NML: Namu_1698
NAKA: H7F38_20695
GOB: Gobs_1358
BSD: BLASA_1168(cysM)
BLAP: MVA48_09490
MMAR: MODMU_1392(cysM)
SEN: SACE_1206(cysM)
SACG: FDZ84_17715
SVI: Svir_29160
SACC: EYD13_16125(cysM)
AMD: AMED_7711(cysK)
AMN: RAM_39620
AMM: AMES_7594(cysK)
AMZ: B737_7594(cysK)
AOI: AORI_6492(cysM)
AJA: AJAP_06505(cysM)
AMQ: AMETH_1416(cysK)
AMYC: CU254_31020(cysM)
AMYB: BKN51_25915(cysM)
AAB: A4R43_36335(cysM)
AMYY: YIM_41670(cysM2)
AORI: SD37_07950(cysM)
AACD: LWP59_06910
APRT: MUY14_45660
AROO: NQK81_33355
ATHM: L1857_09690
ARHD: VSH64_27950
AMOG: QRX60_20915
ACYN: ORV05_26090
PDX: Psed_1511
PSEA: WY02_22440(cysM)
PSEE: FRP1_20220(cysM)
PSEH: XF36_03570(cysM)
PSEQ: AD006_27635(cysM)
PECQ: AD017_07230(cysM)
PHH: AFB00_18205(cysM)
PAUT: Pdca_14350(cysK_1)
PBRO: HOP40_01785
PPEL: H6H00_02435
APRE: CNX65_05080(cysM)
AMI: Amir_1011
SESP: BN6_11660(cysM)
SSYI: EKG83_05910
SACX: IOD16_02920
KAL: KALB_1251
KUT: JJ691_62370(cysK_1)
KBU: Q4V64_19430 Q4V64_35575
KPHY: AOZ06_09770(cysM)
LED: BBK82_06115(cysM)
AHM: TL08_06500
ACTI: UA75_06225
ACAD: UA74_06225
AHG: AHOG_05965(cysM)
ACTA: C1701_06770(cysM)
ALO: CRK62183
PMAD: BAY61_25245(cysM)
SACE: GIY23_05345
ACTU: Actkin_01153(cysM)
CROS: N8J89_35455
ACTY: OG774_27795
UME: RM788_31655
STP: Strop_1102
SAQ: Sare_0991
MAU: Micau_1158
MIL: ML5_1421
MICB: MicB006_1190
MTUA: CSH63_18740(cysM)
MICH: FJK98_05905
MTEM: GCE86_00075
MCAB: HXZ27_07125
MSAG: GCM10017556_37040
VMA: VAB18032_10380
MCRA: ID554_06140
VER: HUT12_06885
MENO: Jiend_16860
MCHL: PVK74_27045
MFEU: H1D33_12505
MPRN: Q3V37_01320
MHAW: RMN56_05510
ASE: ACPL_1167(cysM)
AMS: AMIS_9430
ACTN: L083_1276
AFS: AFR_06350
ACTS: ACWT_1048
AIH: Aiant_53310
ACTR: Asp14428_34510
ACTL: L3i22_010200
ASIC: Q0Z83_078560
AOU: ACTOB_000976
PLK: CIK06_06060(cysM)
PLAB: C6361_13080(cysM)
PLAT: C6W10_12325(cysM)
PFLA: Pflav_060700
PSUU: Psuf_022490
ATL: Athai_51060(cysK)
ASER: Asera_23780(cysK)
PRY: Prubr_12250
CATI: CS0771_03790(cysK_1)
DVC: Dvina_48115
DFU: Dfulv_42645
DROS: Drose_32620
DAUR: Daura_46220
DMAT: Dmats_42665
NHY: JQS43_04175
CCAZ: COUCH_33170
CAI: Caci_7559
SNA: Snas_1541
NAV: JQS30_03005
GLY: K3N28_07475
AEY: CDG81_16665(cysM)
PLAN: A1s21148_01305(cysM)
PLAK: A1s21155_01100(cysM)
PLIM: PHILAsVB114_05915(cysM)
PSUF: A1sIA56_01110(cysM)
PVS: A1sIA79_01045(cysM)
JTL: M6D93_06200
JCY: M6B22_05295
ABAI: IMCC26256_111568
BSOL: FSW04_21915
BALA: DSM104299_04364(cysM)
CWO: Cwoe_1846
PARN: NBH00_12245
SBAE: DSM104329_04137(cysM)
PBAJ: LRS13_21405
TALU: JDY09_07265
AYM: YM304_27740(cysM)
ATQ: GH723_12050
AQZ: KSP35_08285
IAM: HC251_15345
IMA: PO878_08430
DHI: LH044_20245
CALL: OZ401_003182
KBS: EPA93_12695 EPA93_42445
KBB: ccbrp13_62940 ccbrp13_65350(cysM)
TBH: Tbon_07540 Tbon_08090
TFLA: O0235_05220 O0235_07795
MOX: DAMO_1028(cysK)
NAC: AQV86_04805
 » show all
Reference
PMID:18842002
  Authors
O'Leary SE, Jurgenson CT, Ealick SE, Begley TP
  Title
O-phospho-L-serine and the thiocarboxylated sulfur carrier protein CysO-COSH are substrates for CysM, a cysteine synthase from Mycobacterium tuberculosis.
  Journal
Biochemistry 47:11606-15 (2008)
DOI:10.1021/bi8013664
  Sequence
[mtu:Rv1336]
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