Entry
Symbol
mdpB1
Name
methyltransferase [EC:2.1.1.-]
Pathway
map01059 Biosynthesis of enediyne antibiotics
map01110 Biosynthesis of secondary metabolites
Module
M00829 3,6-Dimethylsalicylyl-CoA biosynthesis, malonyl-CoA => 6-methylsalicylate => 3,6-dimethylsalicylyl-CoA
Reaction
R11371 S-adenosyl-L-methionine:6-methylsalicylyl-CoA 3-C-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01059 Biosynthesis of enediyne antibiotics
K21192 mdpB1; methyltransferase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K21192 mdpB1; methyltransferase
Polyketide biosynthesis proteins [BR:ko01008 ]
Polyketide tailoring proteins
Methylase
K21192 mdpB1; methyltransferase
BRITE hierarchy
Genes
Taxonomy UniProt
Reference
Authors
Van Lanen SG, Oh TJ, Liu W, Wendt-Pienkowski E, Shen B
Title
Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.
Journal
Sequence
Reference
Authors
Ling J, Horsman GP, Huang SX, Luo Y, Lin S, Shen B
Title
Enediyne antitumor antibiotic maduropeptin biosynthesis featuring a C-methyltransferase that acts on a CoA-tethered aromatic substrate.
Journal
LinkDB
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