KEGG ORTHOLOGY: K21538

ORTHOLOGY: K21538

Entry

K21538                      KO

Symbol

vTNFR2

Name

Poxvirus tumor necrosis factor receptor II

Pathway

map04061

Viral protein interaction with cytokine and cytokine receptor

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04061 Viral protein interaction with cytokine and cytokine receptor
    K21538  vTNFR2; Poxvirus tumor necrosis factor receptor II
09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K21538  vTNFR2; Poxvirus tumor necrosis factor receptor II
Viral proteins [BR:ko03200]
dsDNA viruses
  Poxviridae
   K21538  vTNFR2; Poxvirus tumor necrosis factor receptor II
Viral network perturbations [br03223.html]
Cytokine-cytokine receptor interaction
  K21538

Genes

VG:

1485875(crmB) 1485876(crmB) 1486070(CrmC) 1486100(CrmD) 1486427(G4R) 1486845(SFV_s002L) 1487004(SFV_s002R) 1670230(MYXV_gp168) 24528036(ACG19_gp002) 24528241(ACG19_gp207) 29057580(BIZ96_gp002) 29057788(BIZ96_gp210) 29063949(BI079_gp002) 29064122(BI079_gp175) 29064152(BI079_gp205) 33867928(CKM52_gp002) 33867934(CKM52_gp008) 33868131(CKM52_gp205) 33868132(CKM52_gp206) 33868133(CKM52_gp001) 33868141(CKM51_gp008) 33868330(CKM51_gp197) 33868331(CKM51_gp001) 65100523(KM542_gp002) 65100740(KM542_gp219) 65100918(KM543_gp176) 65100945(KM543_gp203) 65100949(KM543_gp207) 72551418(OPG002) 72551594(OPG002) 75279559(OPG002) 75279741(OPG002) 928919(OPG002) 929019(OPG002) 932138(m002L) 932503(CamMLVgp210) 932635(CamMLVgp002) 951577(EVM003) 951578(I1R)

Reference

PMID:8091665

Authors

Hu FQ, Smith CA, Pickup DJ

Title

Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor.

Journal

Virology 204:343-56 (1994)
DOI:10.1006/viro.1994.1539

Sequence

[vg:1485875 1485876]

Reference

PMID:8806547

Authors

Smith CA, Hu FQ, Smith TD, Richards CL, Smolak P, Goodwin RG, Pickup DJ

Title

Cowpox virus genome encodes a second soluble homologue of cellular TNF receptors, distinct from CrmB, that binds TNF but not LT alpha.

Journal

Virology 223:132-47 (1996)
DOI:10.1006/viro.1996.0462

Sequence

[vg:1486070]

Reference

PMID:9520445

Authors

Loparev VN, Parsons JM, Knight JC, Panus JF, Ray CA, Buller RM, Pickup DJ, Esposito JJ

Title

A third distinct tumor necrosis factor receptor of orthopoxviruses.

Journal

Proc Natl Acad Sci U S A 95:3786-91 (1998)
DOI:10.1073/pnas.95.7.3786

Sequence

[vg:1486100]

Reference

PMID:8662837

Authors

Schreiber M, Rajarathnam K, McFadden G

Title

Myxoma virus T2 protein, a tumor necrosis factor (TNF) receptor homolog, is secreted as a monomer and dimer that each bind rabbit TNFalpha, but the dimer is a more potent TNF inhibitor.

Journal

J Biol Chem 271:13333-41 (1996)
DOI:10.1074/jbc.271.23.13333

Sequence

[vg:1670230 932138]

Reference

PMID:11119592

Authors

Saraiva M, Alcami A

Title

CrmE, a novel soluble tumor necrosis factor receptor encoded by poxviruses.

Journal

J Virol 75:226-33 (2001)
DOI:10.1128/JVI.75.1.226-233.2001