KEGG   ORTHOLOGY: K21660
Entry
K21660            Tight     KO                                     
Symbol
vBCL2, ORF16
Name
KSHV apoptosis regulator BCL2 homolog
Pathway
map05167  Kaposi sarcoma-associated herpesvirus infection
map05203  Viral carcinogenesis
Network
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06231  Apoptosis (cancer)
nt06524  Apoptosis
nt06532  Autophagy
  Element
N00164  KSHV vBCL2 to crosstalk between extrinsic and intrinsic apoptotic pathways
N00177  KSHV vBCL2 to autophagy-vesicle nucleation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K21660  vBCL2, ORF16; KSHV apoptosis regulator BCL2 homolog
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K21660  vBCL2, ORF16; KSHV apoptosis regulator BCL2 homolog
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K21660  vBCL2, ORF16; KSHV apoptosis regulator BCL2 homolog
Viral proteins [BR:ko03200]
 dsDNA viruses
  Kaposi's sarcoma-associated herpesvirus (Human herpesvirus 8)
   K21660  vBCL2, ORF16; KSHV apoptosis regulator BCL2 homolog
Genes
VG: 4961447(ORF16)
Reference
PMID:25740992
  Authors
Gelgor A, Kalt I, Bergson S, Brulois KF, Jung JU, Sarid R
  Title
Viral Bcl-2 Encoded by the Kaposi's Sarcoma-Associated Herpesvirus Is Vital for Virus Reactivation.
  Journal
J Virol 89:5298-307 (2015)
DOI:10.1128/JVI.00098-15
  Sequence
[vg:4961447]
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