KEGG ORTHOLOGY: K21681

ORTHOLOGY: K21681

Entry

K21681                      KO

Symbol

bcs1

Name

ribitol-5-phosphate 2-dehydrogenase (NADP+) / D-ribitol-5-phosphate cytidylyltransferase [EC:1.1.1.405 2.7.7.40]

Pathway

map00040

Pentose and glucuronate interconversions

map01100

Metabolic pathways

Reaction

R01525

D-ribitol-5-phosphate:NADP+ 2-oxidoreductase

R02921

CTP:D-ribitol-5-phosphate cytidylyltransferase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    K21681  bcs1; ribitol-5-phosphate 2-dehydrogenase (NADP+) / D-ribitol-5-phosphate cytidylyltransferase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.405  ribitol-5-phosphate 2-dehydrogenase (NADP+)
     K21681  bcs1; ribitol-5-phosphate 2-dehydrogenase (NADP+) / D-ribitol-5-phosphate cytidylyltransferase
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.40  D-ribitol-5-phosphate cytidylyltransferase
     K21681  bcs1; ribitol-5-phosphate 2-dehydrogenase (NADP+) / D-ribitol-5-phosphate cytidylyltransferase

Other DBs

COG:	COG1028 COG1211

GO:

0047349

Genes

ECOS:

EC958_3340

KCO:	BWI95_19355

KLU:	K7B04_05685

LEY:	DVA43_14810

HIU:	HIB_11690(bcs1') HIB_11840(bcs1')

ALIG:

NCTC10568_01939(ispD_2)

TBV:	H9L17_00500

PCQ:	PcP3B5_16180(ispD1) PcP3B5_47970(ispD2)

PBAU:

OS670_05290

ALJ:	G8D99_14930

ACIU:

A3K93_11085

SINI:

GT972_07520

WBO:	MIS45_03430

CKE:	B5M06_15305

HYL:	LPB072_04595

HPSE:

HPF_20235(ispD2)

ZMO:

ZMN:

ZMM:

ZMB:

ZMI:

ZMC:	A265_00908(ispD2)

ZMR:	A254_00908(ispD2)

ZMP:	Zymop_0844

HWI:	A0Z60_06675

CCQ:	N149_1385(ispD)

ABL:	A7H1H_2199

ATHR:

ATH_1037

NAM:

NAMH_1606

CPAF:

C6V80_08920(ispD)

PPRF:

DPRO_1984(bcs)

PSEL:

GM415_05370(ispD)

SGR:

SGB:

SFI:

SANL:

SCYE:

SSX:	SACTE_2009

SFA:

Sfla_4295

SDV:	BN159_5701

STRP:

F750_2413

SCI:	B446_13640

SXI:	SXIM_15330

STRC:

AA958_25170

SPRI:

SPRI_4927

SCZ:	ABE83_25180

SCX:	AS200_29490

SRW:	TUE45_03196(ispD1)

SRN:	A4G23_01658(ispD2)

STRT:

A8713_10140

SCLF:

BB341_19490

SGS:	AVL59_40270

STSI:

A4E84_13575

SCAD:

DN051_25530

SPHW:

NFX46_33840

SLS:	SLINC_2989

SNW:	BBN63_23745

SVU:	B1H20_09990

SLAU:

SLA_5894

SNZ:	DC008_11175

SGE:	DWG14_05586(bcs1)

SLK:	SLUN_13130

SDX:	C4B68_26825

SGD:	ELQ87_26380

SQZ:	FQU76_09345

SCYA:

EJ357_15535

STIR:

DDW44_08240

SGZ:	C0216_08925

SVN:	CP980_07690

SNK:	CP967_23320

SHAW:

SFIC:

SGAL:

SSPO:

SPAD:

SFY:	GFH48_26815

SAQU:

SCAV:

SSUB:

SFUG:

STSU:

SCHA:

SCOE:

SBRO:

STUI:

SATA:

SCHF:

SHAR:

SCYG:

S1361_14180(ispD1)

SFEU:

IM697_08240

SLIA:

HA039_23505

SVD:	CP969_14060

SCAL:

I6J39_10210

SFB:	CP974_09315

SPRA:

CP972_12305

SPEU:

CGZ69_11785

SGJ:	IAG43_10235

STRY:

EQG64_09805

SDD:	D9753_23735

SMAO:

SGOB:

SSPN:

SCIR:

SJN:	RI060_28115

SOV:	QZH56_01215

SFIY:

F0344_25070

SKG:	KJK29_25455

SCOA:

QU709_28430

SCHG:

NRO40_09315

SINN:

ABB07_25205

KAB:	B7C62_09600

MOO:	BWL13_02200(bcs1)

MPRT:

MTEC:

MELY:

MEST:

AARC:

AMAU:

DSM26151_09170(bcs1)

ASOI:

MTP13_17175 MTP13_17185

AIL:	FLP10_03170

SALA:

LALL:

NAEI:

ASUF:

PAEY:

JDE:

PHW:	G7075_10580

BLY:	A2T55_13845

BSPO:

L1F31_14280

MPH:	MLP_25850(ispD)

MIK:	FOE78_14050

MICG:

GJV80_06215

NFC:	KG111_01750

PSIM:

KR76_03415

AEZ:	C3E78_05735

AEB:	C6I20_04370

AEF:	GEV26_05500

ASEZ:

H9L21_04570

ADB:	NP095_04525

AWN:	NQV15_05630

MUZ:	H4N58_06600

SGRG:

L0C25_07910

THAO:

NI17_015585

TALX:

FOF52_12610 FOF52_12975

NAL:

B005_2753

NEX:	NE857_05460 NE857_28875

NEC:	KGD82_04090 KGD82_23655

NCG:	KGD84_27880 KGD84_27890

SNAH:

SAIU:

AMAZ:

ACIR:

ACTQ:

SRO:

NCX:	Nocox_05830(ispD2)

NGN:	LCN96_06510

NFS:	OIE67_40495

TBI:

Tbis_0719

MHAI:

OHB01_17350

KBU:	Q4V64_16675

STP:	Strop_1684

SAQ:

Sare_1679

MAU:	Micau_2081

MIL:

MICB:

MTUA:

MICH:

MTEM:

MCAB:

MSAG:

VMA:	VAB18032_13835

MCRA:

ID554_03250

VER:	HUT12_09925

MENO:

MCHL:

MFEU:

MPRN:

MHAW:

PLAB:

PLAT:

CATI:

SNG:	SNE_A02450(ispD)

RHAW:

RPOR:

OTE:

BTH:

BTHO:

Btheta7330_01408(ispD2_2)

BUN:	Bun01g_05870

BHUM:

JXR92_013855

BFC:	BacF7301_03505

BSAL:

K6V25_15340

BDO:	EL88_23930

BDH:	GV66_07440

PCOP:

MICA:

PDI:

MBAS:

FJO:

FFA:	FFWV33_09175

FIA:	NA23_00555(ispD)

TSI:

TPRF:

ABI:

Reference

PMID:11305920

Authors

Zolli M, Kobric DJ, Brown ED

Title

Reduction precedes cytidylyl transfer without substrate channeling in distinct active sites of the bifunctional CDP-ribitol synthase from Haemophilus influenzae.

Journal

Biochemistry 40:5041-8 (2001)
DOI:10.1021/bi002745n

Sequence

[hiu:HIB_11840]

LinkDB

DBGET integrated database retrieval system