KEGG   ORTHOLOGY: K21722
Entry
K21722                      KO                                     
Symbol
ndmA
Name
methylxanthine N1-demethylase [EC:1.14.13.178]
Pathway
map00232  Caffeine metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
Module
M00915  Caffeine degradation, caffeine => xanthine
Reaction
R07955  caffeine:oxygen oxidoreductase (N1-demethylating)
R07956  caffeine:oxygen oxidoreductase (N1-demethylating)
R07957  paraxanthine:oxygen oxidoreductase (N1-demethylating)
R07958  paraxanthine:oxygen oxidoreductase (N1-demethylating)
R07969  1-methylxanthine:oxygen oxidoreductase (N1-demethylating)
R07970  1-methylxanthine:oxygen oxidoreductase (N1-demethylating)
R07973  theophylline:oxygen oxidoreductase (N1-demethylating)
R07974  theophylline:oxygen oxidoreductase (N1-demethylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    K21722  ndmA; methylxanthine N1-demethylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.178  methylxanthine N1-demethylase
     K21722  ndmA; methylxanthine N1-demethylase
Other DBs
COG: COG4638
Genes
PCAF: DSC91_007649
PYE: A6J80_10900
PZH: CX676_16200
ASZ: ASN_2329
PARH: I5S86_05095
IAM: HC251_12390
AG: AFD03116(ndmA)
Reference
PMID:22328667
  Authors
Summers RM, Louie TM, Yu CL, Gakhar L, Louie KC, Subramanian M
  Title
Novel, highly specific N-demethylases enable bacteria to live on caffeine and related purine alkaloids.
  Journal
J Bacteriol 194:2041-9 (2012)
DOI:10.1128/JB.06637-11
  Sequence
[ag:AFD03116]
LinkDB

DBGET integrated database retrieval system