KEGG   ORTHOLOGY: K21724
Entry
K21724                      KO                                     
Symbol
ndmC
Name
7-methylxanthine demethylase [EC:1.14.13.128]
Pathway
map00232  Caffeine metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
Module
M00915  Caffeine degradation, caffeine => xanthine
Reaction
R07965  7-methylxanthine:oxygen oxidoreductase (demethylating)
R07966  7-methylxanthine:oxygen oxidoreductase (demethylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    K21724  ndmC; 7-methylxanthine demethylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.128  7-methylxanthine demethylase
     K21724  ndmC; 7-methylxanthine demethylase
Other DBs
COG: COG4638
Genes
PHF: NLY38_11705
PKJ: Q1W70_26420
BFN: OI25_3683
PCAF: DSC91_007652
PTRO: G5S35_35700
PDIO: PDMSB3_2216
PPAI: E1956_28835
MMS: mma_3678
PARH: I5S86_05125
AG: AFD03118(ndmC)
Reference
PMID:22328667
  Authors
Summers RM, Louie TM, Yu CL, Gakhar L, Louie KC, Subramanian M
  Title
Novel, highly specific N-demethylases enable bacteria to live on caffeine and related purine alkaloids.
  Journal
J Bacteriol 194:2041-9 (2012)
DOI:10.1128/JB.06637-11
  Sequence
[ag:AFD03118]
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