KEGG   ORTHOLOGY: K22434
Entry
K22434            Tight     KO                                     
Symbol
PSIH
Name
tryptamine 4-monooxygenase [EC:1.14.99.59]
Pathway
map00901  Indole alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00962  Psilocybin biosynthesis, tryptophan => psilocybin
Reaction
R11912  tryptamine,hydrogen-donor:oxygen oxidoreductase (4-hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00901 Indole alkaloid biosynthesis
    K22434  PSIH; tryptamine 4-monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.99  Miscellaneous
    1.14.99.59  tryptamine 4-monooxygenase
     K22434  PSIH; tryptamine 4-monooxygenase
Other DBs
COG: COG2124
Genes
PCUB: JR316_0010786
AG: ASU62246(psiH)
Reference
  Authors
Fricke J, Blei F, Hoffmeister D
  Title
Enzymatic Synthesis of Psilocybin.
  Journal
Angew Chem Int Ed Engl 56:12352-12355 (2017)
DOI:10.1002/anie.201705489
  Sequence
LinkDB

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