Entry |
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Symbol |
AF390-400, fmaD
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Name |
5-dehydro-6-demethoxy-6-hydroxyfumagillol O-methyltransferase [EC: 2.1.1.387]
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Pathway |
map00998 | Biosynthesis of various antibiotics |
map01110 | Biosynthesis of secondary metabolites |
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Module |
M00969 | Fumagillin biosynthesis, farnesyl-PP => fumagillin |
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Reaction |
R13123 | S-adenosyl-L-methionine:5-dehydro-6-demethoxy-6-hydroxyfumagillol 6-O-methyltransferase |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00998 Biosynthesis of various antibiotics
K22571 AF390-400, fmaD; 5-dehydro-6-demethoxy-6-hydroxyfumagillol O-methyltransferase
Enzymes [BR:ko01000]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.387 5-dehydro-6-demethoxy-6-hydroxyfumagillol O-methyltransferase
K22571 AF390-400, fmaD; 5-dehydro-6-demethoxy-6-hydroxyfumagillol O-methyltransferase
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Genes |
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Reference |
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Authors |
Lin HC, Tsunematsu Y, Dhingra S, Xu W, Fukutomi M, Chooi YH, Cane DE, Calvo AM, Watanabe K, Tang Y |
Title |
Generation of complexity in fungal terpene biosynthesis: discovery of a multifunctional cytochrome P450 in the fumagillin pathway. |
Journal |
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Sequence |
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LinkDB |
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