KEGG   ORTHOLOGY: K22575
Entry
K22575                      KO                                     
Symbol
AF470
Name
fumagillin biosynthesis monooxygenase
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00969  Fumagillin biosynthesis, farnesyl-PP => fumagillin
Reaction
R13147  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K22575  AF470; fumagillin biosynthesis monooxygenase
Genes
FPOA: FPOAC1_010773
FVN: FVRRES_11776
FFC: NCS54_01151100
FKR: NCS57_01141500
FMU: J7337_002792
PCHM: VFPPC_05888
AMUS: LMH87_002446
AFM: AFUA_8G00470
NFI: NFIA_093950
Reference
PMID:24568283
  Authors
Lin HC, Tsunematsu Y, Dhingra S, Xu W, Fukutomi M, Chooi YH, Cane DE, Calvo AM, Watanabe K, Tang Y
  Title
Generation of complexity in fungal terpene biosynthesis: discovery of a multifunctional cytochrome P450 in the fumagillin pathway.
  Journal
J Am Chem Soc 136:4426-36 (2014)
DOI:10.1021/ja500881e
  Sequence
[afm:AFUA_8G00470]
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