KEGG   ORTHOLOGY: K22775
Entry
K22775                      KO                                     
Symbol
UL122
Name
Cytomegalovirus viral transcription factor IE2
Pathway
map05163  Human cytomegalovirus infection
Network
nt06167  Human cytomegalovirus (HCMV)
nt06516  TNF signaling
  Element
N00387  HCMV IE1-72/IE2-86 to PI3K signaling pathway
N00398  HCMV IE2-86 to TNF-NFKB signaling pathway
N00420  HCMV IE2-86 to p21-cell cycle G1/S
N00421  HCMV IE2-86 to p21-cell cycle G1/S
N00422  HCMV IE2-86 to cell cycle G1/S
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K22775  UL122; Cytomegalovirus viral transcription factor IE2
 09180 Brite Hierarchies
  09185 Viral protein families
   03200 Viral proteins
    K22775  UL122; Cytomegalovirus viral transcription factor IE2
Viral proteins [BR:ko03200]
 dsDNA viruses
  Human cytomegalovirus (Human herpesvirus 5)
   K22775  UL122; Cytomegalovirus viral transcription factor IE2
Genes
VG: 11464176(UL122) 11464334(UL122) 24284831(AA805_gp26) 25026518(UL122) 3077563(UL122) 30855120(BWV06_gp108) 921233(THVgp150) 935457(UL122)
Reference
PMID:21865379
  Authors
Burgdorf SW, Clark CL, Burgdorf JR, Spector DH
  Title
Mutation of glutamine to arginine at position 548 of IE2 86 in human cytomegalovirus leads to decreased expression of IE2 40, IE2 60, UL83, and UL84 and increased transcription of US8-9 and US29-32.
  Journal
J Virol 85:11098-110 (2011)
DOI:10.1128/JVI.05315-11
  Sequence
[vg:3077563]
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