KEGG   ORTHOLOGY: K23990
Entry
K23990            Tight     KO                                     
Symbol
NEPS1
Name
nepetalactol dehydrogenase / (+)-cis,trans-nepetalactol synthase [EC:1.1.1.419 5.5.1.34]
Pathway
map00902  Monoterpenoid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R12520  (S)-8-oxocitronellyl enol cyclase [(+)-cis,trans-nepetalactol-forming]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00902 Monoterpenoid biosynthesis
    K23990  NEPS1; nepetalactol dehydrogenase / (+)-cis,trans-nepetalactol synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.419  nepetalactol dehydrogenase
     K23990  NEPS1; nepetalactol dehydrogenase / (+)-cis,trans-nepetalactol synthase
 5. Isomerases
  5.5  Intramolecular lyases
   5.5.1  Intramolecular lyases (only sub-subclass identified to date)
    5.5.1.34  (+)-cis,trans-nepetalactol synthase
     K23990  NEPS1; nepetalactol dehydrogenase / (+)-cis,trans-nepetalactol synthase
Genes
AG: AXF35971(NEPS1)
Reference
  Authors
Lichman BR, Kamileen MO, Titchiner GR, Saalbach G, Stevenson CEM, Lawson DM, O'Connor SE
  Title
Uncoupled activation and cyclization in catmint reductive terpenoid biosynthesis.
  Journal
Nat Chem Biol 15:71-79 (2019)
DOI:10.1038/s41589-018-0185-2
  Sequence
LinkDB

DBGET integrated database retrieval system